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102 recruiting studies matching your filters

Neurologic Bone Marrow Derived Stem Cell Treatment Study

This is a human clinical study involving the isolation of autologous bone marrow derived stem cells (BMSC) and transfer to the vascular system and inferior 1/3…

Neurologic DisordersNervous System DiseasesNeurodegenerative Diseases+23 more

Estimated

~$10 – $7,500

MD Stem CellsNCT02795052

TRANSPIRE: Lung Injury in a Longitudinal Cohort of Pediatric HSCT Patients

Hematopoietic stem cell transplant (HSCT) is an effective but toxic therapy and pulmonary morbidity affects as many as 25% of children receiving transplant. Ea…

Hematopoietic Stem Cell Transplant (HSCT)Diffuse Alveolar HemorrhageThrombotic Microangiopathies+2 more

Estimated

~$10 – $675

Children's Hospital Medical Center, CincinnatiNCT04098445

Phase 1

Safety of Combined Therapy With Erythropoietin and Melatonin for Very Preterm Infants With Intraventricular Hemorrhage (SCEMPI)

Very preterm infants are prone to numerous medical complications with lifelong impact. Amongst the most serious neurologically are white matter injury (WMI), i…

Intraventricular Hemorrhage of Prematurity

Estimated

~$10 – $6,250

Johns Hopkins UniversityNCT05617833

Cryo-FIRST: Cryoprecipitate For Immediate Resuscitation in Severe Trauma: Effectiveness of Pathogen Reduced Cryoprecipitated Fibrinogen Complex (INTERCEPT Fibrinogen Complex, IFC) for Treatment of Trauma Associated Hemorrhage

The objective of this multicenter, single-arm, observational study is to determine the feasibility and effectiveness of early administration of FDA-approved, p…

HypofibrinogenemiaHemorrhageTrauma Associated Hemorrhage+1 more

Estimated

~$10 – $8,750

Cerus CorporationNCT07218185

Phase 4

Prophylactic Tranexamic Acid for Second Trimester Dilation and Evacuation and Bleeding Outcomes: A Randomized Controlled Trial

Although procedural abortion in the second trimester is extremely safe, hemorrhage is one of the leading causes of morbidity and mortality. Tranexamic acid (TX…

AbortionDilation and EvacuationHemorrhage+2 more

Estimated

~$10 – $6,250

University of California, San DiegoNCT06820177

Observational

STORM: Safety, Feasibility, and Efficacy of Non-invasive Vagus Nerve Stimulation (nVNS) in the Treatment of Aneurysmal Subarachnoid Hemorrhage

This is a single-site, single-arm, open-label pilot study assessing the safety, feasibility, and efficacy of non-invasive vagus nerve stimulation (nVNS), gamma…

Subarachnoid Hemorrhage, Aneurysmal

Estimated

~$10 – $6,250

Massachusetts General HospitalNCT05103566

Phase 4

Intranasal Sphenopalatine Ganglion Blockade as a Non-invasive, Opioid-sparing Treatment for Headaches Following Aneurysmal Subarachnoid Hemorrhage

In patients with bleeding from a brain aneurysm, severe headache is the most common complaint. However, the pain is difficult to treat. The use of standard pai…

Aneurysmal Subarachnoid Hemorrhage (aSAH)Headache

Estimated

~$10 – $6,250

Wright State UniversityNCT07116408

Recovery of Consciousness Following Intracerebral Hemorrhage

The objectives of the RECONFIG clinical study are to : 1. To identify the time to the first diagnosis of cognitive motor dissociation (CMD) in intracerebral h…

Intra Cerebral Hemorrhage

Estimated

~$10 – $750

Columbia UniversityNCT03990558

Nitric Oxide Consumption as a Predictor of Vasospasm in Subarachnoid Hemorrhage (SAH): a Prospective Observational Study

The goal of this observational study is to understand if angiographic cerebral vasospasm (CV) can be predicted by levels of nitric oxide (NO) consumption in pa…

Aneurysmal Subarachnoid HemorrhageCerebral Vasospasm

Estimated

~$10 – $750

Massachusetts General HospitalNCT07614906

Observational

Non-Invasive Cerebral Autoregulation Monitoring Validation and Autonomic Modulation in Aneurysmal Subarachnoid Hemorrhage: A Two-Component Prospective Study of EVD Clamping Validation, CA Natural History, and the Effects of Cervical Sympathetic Block and Transcutaneous Auricular Vagal Nerve Stimulation on Cerebral Autoregulation Parameters

This is a two-component prospective study of adult aneurysmal subarachnoid hemorrhage (aSAH) patients admitted to the Neurosciences Intensive Care Unit (NSICU)…

Subarachnoid Hemorrhage, AneurysmalDelayed Cerebral IschemiaCerebral Vasospasm+1 more

Estimated

~$10 – $6,250

University of Texas Southwestern Medical CenterNCT07577739

Prospective, Open-Label, Multi-Center ProceDural Data CollectIon Case Registry on NeVa VS for CerebraL VAsospasm ManagemenT in Post SAH PatiEnts (The DILATE Registry)

A multi-center, observational registry study intended to assess the HDE-approved NeVa VS cerebral artery dilation device in patients with symptomatic cerebral …

Cerebral VasospasmAneurysmal Subarachnoid Hemorrhage (aSAH)

Estimated

~$10 – $1,125

VesalioNCT06893588

Prospective Observational Multimodal Neuromonitoring in Adult Neurosciences Intensive Care Unit Patients: Characterization of Noninvasive Cerebral Autoregulation Indices, Quantitative EEG, and Physiologic Correlates Across NSICU Diagnoses

This is a prospective observational cohort study of adult patients admitted to the Neurosciences Intensive Care Unit (NSICU) at UT Southwestern Medical Center.…

Subarachnoid Hemorrhage, AneurysmalBrain Injuries, TraumaticCerebral Hemorrhage+3 more

Estimated

~$10 – $750

University of Texas Southwestern Medical CenterNCT07577713