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266 recruiting studies matching your filters

Superiority of Phenylephrine Versus Norepinephrine in Complex Spine Surgery (SPiNeS): A Prospective Randomized Superiority Trial

The purpose of this research is to compare two commonly used medications, phenylephrine and norepinephrine, that are used to treat low blood pressure during co…

Spine SurgeryIntraoperative HypotensionTissue Perfusion

Estimated

~$25 – $1,000

Actual pay is set by the research site.

Mayo ClinicNCT07796282

Phase 1

Safety and Feasibility of On-Site Manufacture of CD19 CAR T Cells Using the CliniMACS Prodigy in Pediatric and Young Adult Patients With Relapsed/Refractory CD19 Positive Acute Lymphoblastic Leukemia and Non-Hodgkin's Lymphoma

This pilot study examines the safety and efficacy of anti-CD19 CAR T cells manufactured on-site in children and young adults with relapsed or refractory CD19+ …

Acute Lymphoblastic Leukemia, in RelapseNon-Hodgkin's Lymphoma, RelapsedNon-Hodgkin's Lymphoma Refractory+3 more

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Nationwide Children's HospitalNCT05779930

Phase 2

Bacterial Decolonization Plus Intraoperative Indocyanine Green Angiography for Soft Tissue Sarcomas of the Lower Extremity Receiving Preoperative Radiotherapy (CONCERTO)

This trial will investigate the combination of two low-cost, non-toxic strategies to assess whether they can reduce the risk of acute major wound complications…

Sarcoma,Soft Tissue

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Adam OlsonNCT06712433

Observational

A Unified Protocol to Address Sexual Minority Women's Minority Stress, Mental Health and Hazardous Drinking

The purpose of this 2-arm randomized controlled trial is to assess the efficacy of a 10-session lesbian, gay, bisexual, transgender, and queer (LGBTQ)-affirmat…

Heavy DrinkingMental Health Issue

Estimated

~$10 – $750

Actual pay is set by the research site.

Yale UniversityNCT05509166

Observational

Bridging Adolescent and Young Adult Sarcoma Survivors With Personalized Oncology Exercise Service (AYA-ONE): A Pilot Intervention

This study will evaluate strategies to improve physical function and promote exercise and physical activity in adolescents and young adults (AYAs) with sarcoma…

SarcomaBone SarcomaSoft Tissue Sarcoma (STS)

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Dana-Farber Cancer InstituteNCT07662239

Observational

A Multi-Site, Parallel-Group, Randomized Clinical Trial Comparing a Brief Tele-Cognitive Behavioral Therapy Intervention (BRIGHT) With Attention Control for the Reduction of Body Image-Related Distress Among Head and Neck Cancer Survivors

In this multi-center randomized clinical trial, head and neck cancer (HNC) survivors with clinically significant body image distress (BID) (N=180) will be rand…

Head and Neck CancerBody Image DisturbanceBody Image+3 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Medical University of South CarolinaNCT05442957

Observational

Early Feasibility Study of the GORE® Multibranch Arch Endoprosthesis (MBA Device)

The MBA 25-04 study is a prospective, multicenter, non-randomized, single-arm, early feasibility study designed to assess the initial safety of the MBA device …

Thoracic Aortic AneurysmPenetrating Aortic Ulcers (PAUs)Thoracic Aortic Dissection+1 more

Estimated

~$10 – $1,125

Actual pay is set by the research site.

W.L.Gore & AssociatesNCT07564375

Phase 1

Positron Emission Tomography (PET) Imaging of the Enhanced Permeability and Retention (EPR) Effect With [89Zr]DFO-starPEG in Patients With Solid Tumors

This is a first-in-human, pilot study of the novel PET-imaging radiotracer \[89Zr\]DFO-starPEG. The study is designed to obtain preliminary data to support fut…

Solid TumorSolid CarcinomaSoft Tissue Lesion

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Robert Flavell, MD, PhDNCT06894745

Defining the Basis of Fibromuscular Dysplasia: The Define-FMD Study

The purpose of this study has evolved and expanded since its inception. Originally the intent was to establish the functional, molecular and genetic profile of…

Fibromuscular DysplasiaSpontaneous Coronary Artery DissectionCervical Artery Dissection

Estimated

~$10 – $750

Actual pay is set by the research site.

Icahn School of Medicine at Mount SinaiNCT01967511

Phase 4

Restoring Facial Volume After GLP-1 Weight Loss With Radiesse

The goal of this clinical trial is to evaluate the potential of Calcium Hydroxylapatite (CaHA) to restore facial volume and improve skin quality in patients wi…

Volume Loss (Soft Tissue Ptosis or Atrophy )

Estimated

~$25 – $1,500

Actual pay is set by the research site.

Kalpna Kay Durairaj, MD, FACSNCT07419854

Phase 2

A Phase 2, Multicenter, Open-label Study of Lifileucel (Tumor-infiltrating Lymphocytes [TIL]) in Participants With Previously Treated Advanced Soft Tissue Sarcoma

A study of lifileucel (tumor-infiltrating lymphocytes) in adults with advanced soft tissue sarcoma ('SARATOGA')

SarcomaSoft Tissue Sarcoma (STS)Advanced Soft Tissue Sarcoma+2 more

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Iovance Biotherapeutics, Inc.NCT07741877

Phase 2

Preoperative 5-Day Radiotherapy for Soft Tissue Sarcoma: A Single Institution Phase II Trial

The purpose of this research study is to preserve healthy tissue around the cancer on the arm(s) and/or leg(s) using Hypofractionated radiotherapy, while treat…

Soft Tissue Sarcoma

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Medical University of South CarolinaNCT06905132