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501 recruiting studies matching your filters

Trial to Reduce Antimicrobial Use In Nursing Home Residents With Alzheimer's Disease and Other Dementias 2.0 (TRAIN-AD 2.0)

The goal of this pragmatic cluster randomized clinical trial is to compare management of suspected infection in nursing home residents with dementia The main q…

DementiaAlzheimer DiseaseInfections

Estimated

~$10 – $7,500

Hebrew SeniorLifeNCT05950607

Phase 1

PET Imaging of Radiolabeled Anti-HIV-1 Envelope Monoclonal Antibody (VRC01)

This is a single center exploratory imaging study involving one intravenous microdose of 89Zr-DFO-VRC01 followed by whole-body PET-MR imaging in HIV infected i…

HIV-1-infection

Estimated

~$10 – $5,625

University of California, San FranciscoNCT03729752

Phase 2

Cholesterol and Inflammation Lowering Via Bempedoic Acid, an ACL-inhibiting Regimen in HIV Trial (CLEAR HIV Trial)

This is a randomized placebo-controlled study in treated and suppressed HIV-infected individuals aged ≥40 years with either known CVD or 1 CVD risk factor to s…

DyslipidemiasCardiovascular DiseasesHIV Infections+1 more

Estimated

~$10 – $7,500

Priscilla Hsue, MDNCT05488431

Phase 4

Ferumoxytol Nanozymes for Biofilm Disruption: A Clinical Study

The antimicrobial efficacy and healing potential of clinically approved ferumoxytol nanozymes versus the standard 3% NaOCl irrigant will be evaluated in adults…

Apical PeriodontitisEndodontic DiseaseRoot Canal Infection

Estimated

~$10 – $6,250

University of PennsylvaniaNCT07518901

Predictors of Post-COVID Clinical and Cognitive Consequences

The CDC describes Post-acute sequelae of SARS-COV-2 infection (PASC) for the wide range of physical and mental health consequences experienced by some patients…

Post Acute Sequelae of SARS CoV 2 InfectionObstructive Sleep Apnea

Estimated

~$10 – $675

VA Office of Research and DevelopmentNCT06291870

Phase 2

Alanyl-glutamine Supplementation of Standard Treatment for C. Difficile Infection: a Randomized, Double-blind, Placebo-controlled Trial

This is a randomized, double-blind, placebo-controlled trial to determine the optimal dose and safety of oral alanyl-glutamine between 4, 24, and 44 g doses ad…

Clostridioides Difficile InfectionClostridium Difficile InfectionClostridium Difficile Diarrhea+1 more

Estimated

~$10 – $6,250

University of VirginiaNCT04305769

Phase 3

The Effect of Pre-Operative Bacterial Decolonization on Post-Operative Infection Rate for Lower Extremity Wounds Healing by Second Intention

The goal of this clinical trial is to learn if reducing bacterial load on the skin and nostrils with topical antibacterial soap and ointment, respectively, red…

Surgical Wound Infection

Estimated

~$10 – $6,250

The Cooper Health SystemNCT07142408

Observational

Examining the Effect of High-Intensity Exercise to Attenuate Cognitive Function Limitations and Train Exercise Habits in Older People Living With HIV (HEALTH-Cog)

People aging with HIV are at higher risk for Alzheimer's disease and related dementias, and although physical activity is a promising target to mitigate such r…

HIV InfectionsCognitive Impairment

Estimated

~$10 – $6,250

University of Alabama at BirminghamNCT06013579

Observational

Prediction and Reduction of Central Line Associated Blood Stream Infections: A Machine Learning Improvement Study

Prospective, multi-center, cluster-randomized trial of a hospital Infection Preventionist (IP)-led quality improvement study to provide clinical teams with jus…

Central Line Associated Blood Stream Infections (CLABSI)

Estimated

~$10 – $6,250

Swedish Medical CenterNCT07108660

Phase 1

A Multicenter, Open-label, Phase 1b Study to Assess the Pharmacokinetics, Safety, and Tolerability of Sulbactam-Durlobactam in Hospitalized Pediatric Patients From Birth to <18 Years Who Are Receiving Systemic Antibiotic Therapy for Suspected or Confirmed Acinetobacter Baumannii-calcoaceticus Complex Infection

The goal of this clinical trial is to investigate the use of Sulbactam-Durlobactam (SUL-DUR) in pediatric patients and is being conducted to collect pharmacoki…

Acinetobacter Baumannii-calcoaceticus Complex Infection (ABC)

Estimated

~$10 – $8,750

Innoviva Specialty TherapeuticsNCT06801223

Phase 1

A Phase I/IIa, Randomized, Double Blind, Placebo Controlled, Dose Escalation and Cohort Expansion Study to Evaluate the Safety, Tolerability, Immunogenicity, and Efficacy of NWRD09 Injection in Female Participants With Persistent HPV16 Infection

This is a two-part, phase I/IIa study, intended to evaluate the safety, tolerability, immunogenicity, and efficacy of NWRD09 in female participants with persis…

Persistent HPV16 Infection

Estimated

~$10 – $8,750

Newish Biotech (Wuxi) Co., Ltd.NCT07536282

Observational

Syringe Service Based Telemedicine and Social Network Driven HIV Prevention Service Implementation

The goal of this clinical trial is to evaluate the effectiveness of a social network intervention to recruit people who inject drugs and their networks for HIV…

HIV InfectionsSubstance Use DisordersAddiction+3 more

Estimated

~$10 – $6,250

Johns Hopkins UniversityNCT06103370