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Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE): The Role of Angiotensin-(1-7) in Hypertension and Hypertension-Induced Heart and Kidney Damage
Studying the causal roles of components of the renin-angiotensin-aldosterone system (including angiotensin-(1-7) (Ang-(1-7)), angiotensin-converting enzyme 2 (…
HypertensionLeft Ventricular HypertrophyLeft Ventricular Dysfunction+15 more
Wake Forest University Health SciencesNCT04752293
Observational
Incremental Hemodialysis for Veterans in the First Year of Dialysis (IncHVets): A Pragmatic, Multi-Center, Randomized Controlled Trial
In this pragmatic clinical trial, which will dovetail with Veterans' routine outpatient dialysis clinic visits in six VA medical centers, the investigators wil…
Chronic Kidney Disease (CKD) Stage 5Kidney Dysfunction Requiring Dialysis (KDRD)Dialysis Dependency
VA Office of Research and DevelopmentNCT05465044
Phase 1
Development of a Clinical Experimental Heat Stress Protocol and Exploration of the Effect of Niacinamide on Physiologic, Metabolic, and Biochemical Responses to Heat Stress
The goal of this clinical trial is to learn about the processes occurring in the kidneys while under heat stress in healthy volunteers. The main questions it a…
Heat StrainHealthy Volunteer StudyKidney Dysfunction
Beth Israel Deaconess Medical CenterNCT06983730