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Cold and Compression After Total Knee Arthroplasty for Pain Attenuation: A Randomized, Controlled Trial
The purpose of this study is to compare pain score (Patient-Reported Outcomes Measurement Information System: PROMIS NRS Pain Subscale) between the control and…
Yale Steroid Enhanced Versus Exparel Nerveblock TKA Randomized Controlled Trial (RCT) Study
The objective of this phase 2 study is to investigate the efficacy of Dexamethasone sodium phosphate (DEX) plus Methylprednisolone acetate (MPA) in combination…
Swelling Management After Total Knee Arthroplasty: A Randomized Controlled Trial
To determine if inelastic adjustable compression garment results in improved surgical limb swelling control (bioimpedance assessment - primary outcome) after T…
Binaural Beats vs Music of Choice for Early Postoperative Pain After Ambulatory Total Knee and Total Hip Arthroplasty: A Randomized Controlled Trial
To deliver a 30-minute binaural beats audio intervention in PACU and collect pain and anxiety outcomes immediately following surgery, and 4 hours following sur…
Optimizing a Remote-based Physical Activity Intervention for Adults With Total Knee Replacement
The purpose of this study is to identify which supplemental intervention components added to an online exercise program contribute to the greatest increases in…
Cannabidiol for Postoperative Opioid Reduction in Primary Total Knee Arthroplasty - a Randomized, Two by Two Factorial, Double-blind, Placebo-controlled Clinical Trial
The goal of this study is to better understand how daily treatment with cannabidiol (CBD) affects the need for opioid pain medication, as well as pain, inflamm…
Suzetrigine for Treatment and Reduction of Intense Discomfort After knEe Replacement PAIN
This is a prospective, randomized study. The purpose of this study is to evaluate if the addition of Suzetrigine, a new pain medication, to well established pe…
Evaluating the Impact of Remote Therapeutic Monitoring on Knee Arthroplasty Recovery
The main goal of this study is to see if there is a connection between the social and economic resources available in a patient's neighborhood (measured by the…
The Feasibility of a Nurse-Initiated Weighted Blanket in Orthopedic Surgical Patients Undergoing Total Knee Arthroplasty: A Pilot Study
The purpose of this study is to explore the acceptability and feasibility of weighted blankets in total knee replacement (TKR) patients. The study also aims to…
An Open Label Data Collection Study of My Connect Post-Op, a Post-Operative Communication Tool
This open label, multi-center study will collect data from the participant's use of My Connect Post-Op Software as a post-operative communication solution in s…
Yale Steroid Enhanced Versus Exparel Nerveblock TKA Part 2
The objective of this study is to investigate the efficacy of Dexamethasone sodium phosphate plus Methylprednisolone acetate in combination with plain bupivaca…