The purpose of this research study is to examine how well a medication called lumateperone (Caplyta) works to relieve depression in older adults with treatment…

Treatment Resistant Depression (TRD)Late Life Depression (LLD)Depression / Major Depressive Disorder

~Estimated

~$10 – $7,500

Eric LenzeNCT07623135

Observational

High-Dose Spaced Bilateral tDCS for Late-Life Depression: Open-Label Pilot Study

The purpose of this research study is to determine the effectiveness of Transcranial direct current stimulation (tDCS) therapy in the treatment of participants…

Late Life Depression (LLD)

~Estimated

~$10 – $7,500

Andre Russowsky BrunoniNCT07657234

Characterizing Cognitive Decline in Late Life Depression: The Alzheimer's Disease Neuroimaging Initiative - Depression Project

The purpose of this research study is to characterize the mechanisms contributing to cognitive impairment and accelerated cognitive decline in Late Life Depres…

Major DepressionLate Life Depression (LLD)

~Estimated

~$10 – $750

University of Southern CaliforniaNCT02434393