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6 recruiting studies matching your filters

A Phase I Study of Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, and Other Hematologic Malignancies

Background: Blood cancers (such as leukemias) can be hard to treat, especially if they have mutations in the TP53 or RAS genes. These mutations can cause the …

Malignancy, HematologicNeoplasms, HematologicNeoplasms, Hematopoietic+8 more

Estimated

~$150 – $2,700

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT06904066

Phase 1

A Pilot/Phase 1 Study of Immunosuppression-free Regulatory T-cell Graft-engineered Haploidentical Hematopoietic Cell Transplantation in Relapsed/Refractory and Ultra-High-risk AML/MDS

This research study is evaluating the safety and efficacy of the IS-free Treg-cell graft-engineered haplo transplant method in people with relapsed/refractory …

Stem Cell Transplant ComplicationsGraft Vs Host DiseaseMyeloid Leukemia, Acute+2 more

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Dana-Farber Cancer InstituteNCT04678401

Observational

ACCESS-Leukemia: Addressing Cancer Care Equity With Social Determinants of Health Screening and Early Intervention

The purpose of this study is to explore if screening health-related social needs and early social work consultation is feasible and acceptable for adults with …

Leukemia, Acute

Estimated

~$10 – $750

Actual pay is set by the research site.

Massachusetts General HospitalNCT07671209

Phase 1

Phase I/II Trial of Anti-CD19 Chimeric Antigen Receptor T-Cell Immunotherapy for B-cell Leukemias

Background: Chronic lymphocytic leukemia (CLL),small lymphocytic lymphoma (SLL) and B-cell acute lymphoblastic leukemia or lymphoma (ALL) are blood cancers th…

Leukemia, Lymphocytic, Chronic, B-CellB-Lymphocytic Leukemia, ChronicB-Cell Chronic Lymphocytic Leukemia+4 more

Estimated

~$150 – $2,700

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT06364423

Observational

A Decisional Intervention for Older Adults With Acute Myeloid Leukemia and Their Caregivers

This is a multicenter randomized controlled trial that assesses the efficacy of a decisional intervention \[University of Rochester-Geriatric Oncology assessme…

OncologyMyeloid Leukemia, AcuteCancer

Estimated

~$10 – $750

Actual pay is set by the research site.

University of RochesterNCT06697600

Prospective Analysis of Frailty Phenotype Assessments to Optimize Treatment Strategies for Older Patients With Hematologic Malignancies

The purpose of this research study is to determine if frailty assessments can be used to predict how well patients aged 60 years and older will do after chemot…

Leukemia, AcuteMDS

Estimated

~$10 – $750

Actual pay is set by the research site.

Abramson Cancer Center at Penn MedicineNCT03680677