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333 recruiting studies matching your filters

Evaluate the Molecular Mechanisms of HMB-enriched Amino Acid Supplement to Reverse Muscle Loss in Patients With Alcoholic Liver Disease and COVID-19

Patients with COVID-19 and comorbidities including alcohol associated liver disease (ALD) are at risk for severe illness and abrupt or sudden clinical deterior…

Alcoholic Liver DiseaseCOVID 19 Pneumonia

Estimated

~$10 – $6,250

The Cleveland ClinicNCT04858412

Comparison of ALD, NASH, and Healthy Control Patients

The availability of biological samples from individuals with alcoholic liver disease (ALD), as well as samples from appropriate heavy drinking, yet healthy con…

ALD - Alcoholic Liver Disease

Estimated

~$10 – $750

The Cleveland ClinicNCT03224949

Phase 1

A Phase 1/1b Single Arm Safety Lead in Study of Leronlimab (CCR5 Blockade) With Hepatic Arterial Infusion Pump Therapy Delivering Floxuridine (FUDR) and Concurrent Systemic Therapy in Colorectal Cancer Liver Metastases Patients (CHAMP)

This phase I/Ib trial tests the effect of leronlimab in combination with hepatic arterial infusion (HAI) floxuridine (FUDR)and standard of care (SOC) systemic …

Metastatic Colorectal CarcinomaMetastatic Malignant Neoplasm in the LiverStage IV Colorectal Cancer AJCC v8

Estimated

~$10 – $6,250

City of Hope Medical CenterNCT07842965

Phase 4

National Liver Cancer Screening Trial

The National Liver Cancer Screening Trial is an adaptive randomized phase IV Trial comparing ultrasound-based versus biomarker-based screening in 5500 patients…

Carcinoma, HepatocellularLiver CancerLiver Cirrhosis+1 more

Estimated

~$10 – $6,250

University of Texas Southwestern Medical CenterNCT06084234

Effectiveness of T-DXd Across HER2-positive Solid Tumors in Patients Who Have Received Prior Systemic Treatment and Have no Satisfactory Alternative Treatment Options: A Hybrid Observational Study

This study will evaluate the effectiveness of T-DXd in patients with HER2-positive (IHC 3+) locally advanced, unresectable, or metastatic solid tumors who have…

Adenocarcinoma (NOS)Anal CancerBladder Cancer+24 more

Estimated

~$10 – $1,125

AstraZenecaNCT07124000

Phase 3

A Randomized Phase III Study of Systemic Therapy With or Without Hepatic Arterial Infusion for Unresectable Colorectal Liver Metastases: The PUMP Trial

This phase III trial compares hepatic arterial infusion (HAI) (pump chemotherapy) in addition to standard of care chemotherapy versus standard of care chemothe…

Metastatic Colorectal CarcinomaMetastatic Malignant Neoplasm in the LiverStage IV Colorectal Cancer AJCC v8+1 more

Estimated

~$10 – $7,500

ECOG-ACRIN Cancer Research GroupNCT05863195

Phase 4

The BUMP Trial: Intrathecal Buprenorphine Versus Morphine for Postcesarean Analgesia-A Randomized Noninferiority Trial

In this study the researchers are randomizing pregnant patients coming for elective cesarean delivery to receive either intrathecal buprenorphine or morphine f…

Cesarean Delivery

Estimated

~$10 – $6,250

Icahn School of Medicine at Mount SinaiNCT07786012

Phase 2

Impact of Soymilk on Liver Disease Severity of Children With Non-alcoholic Fatty Liver Disease (NAFLD)

A randomized, controlled study of standard soy milk consumption compared to 2% fat cow's milk consumption in children with Non-alcoholic Fatty Liver Disease (N…

Non-Alcoholic Fatty Liver Disease

Estimated

~$10 – $7,500

Marialena MouzakiNCT06133101

Observational

Supporting Just-In-Time Consent for Prenatal Screening: The INFORM Study

This clinical trial is about prenatal genetic screening. It will test an intervention to help people make decisions about screening. The intervention is a shor…

Delivery of Health CareGenetic TestingHumans+9 more

Estimated

~$10 – $6,250

Case Western Reserve UniversityNCT07557303

Phase 3

A Master Protocol for a Randomized, Controlled, Clinical Trial of Multiple Pharmacologic Agents in Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease Who Are at Increased Risk of Developing Major Adverse Liver Outcomes

The main purpose of the SYNERGY-OUTCOMES study is to find out whether retatrutide and tirzepatide can prevent major adverse liver outcomes (MALO) in people wit…

Metabolic Dysfunction-Associated Steatotic Liver Disease

Estimated

~$10 – $7,500

Eli Lilly and CompanyNCT07165028

Protoacoustic Imaging for 3D Mapping the Bragg Peak in Real Time During Proton Therapy (PROTEUS)

The purpose of this study is to test a new imaging technology called radioacoustic imaging (RAI) that may help doctors see where radiation is being delivered d…

Proton TherapyRadiation Therapy, Secondary Skin ReactionsLiver Cancer+1 more

Estimated

~$10 – $750

University of OklahomaNCT07832617

Observational

Facilitating the Engagement and Satisfaction of Older Adults in Their Cancer Care Planning: A Randomized Study to Understand the Preferences and Views of Older Adults Regarding the Use of Geriatric and Objective Functional Assessments for Cancer Treatment Planning

This Interventional clinical study aims to explore how receiving information about their health and physical abilities affects the treatment decisions of older…

Care DeliveryGeriatricsGeriatric Assessment

Estimated

~$10 – $6,250

Fox Chase Cancer CenterNCT06652347