Browse studies

Find your next paid study

9 recruiting studies matching your filters

Evaluation of 18F-Fluciclovine PET-MRI as a Biomarker of Response in Pediatric and Young Adult Patients With Low Grade Gliomas (LGG)

The purpose of this study is to see if 18F-Fluciclovine (Axumin®) is useful and safe in the management of children with Low Grade Gliomas (LGG). Imaging with 1…

GliomaLow-grade GliomaLow Grade Glioma of Brain+2 more

Estimated

~$10 – $6,250

Children's Hospital of PhiladelphiaNCT05555550

Phase 3

A Phase 3 Randomized Non-Inferiority Study of Carboplatin and Vincristine Versus Selumetinib (NSC# 748727) in Newly Diagnosed or Previously Untreated Low-Grade Glioma (LGG) Not Associated With BRAFV600E Mutations or Systemic Neurofibromatosis Type 1 (NF1)

This phase III trial compares the effect of selumetinib versus the standard of care treatment with carboplatin and vincristine (CV) in treating patients with n…

Low Grade AstrocytomaLow Grade GliomaMetastatic Low Grade Astrocytoma+3 more

Estimated

~$10 – $5,625

National Cancer Institute (NCI)NCT04166409

Phase 2

A Phase 2 De-escalation Study of Dabrafenib and Trametinib for Patients With BRAF V600 Mutant Low-Grade Gliomas

This phase II trial studies how well de-escalating the drugs dabrafenib and trametinib works in treating patients with low-grade gliomas that have a BRAF V600 …

BRAF V600 MutationLow-grade GliomaLow Grade Glioma of Brain+1 more

Estimated

~$10 – $5,625

University of California, San FranciscoNCT07110246

Phase 1

ViCToRy: Vorasidenib in Combination With Tumor Specific Peptide Vaccine for Recurrent IDH1 Mutant Lower Grade Gliomas

The purpose of this study is to determine the safety and efficacy of a PEPIDH1M vaccine in combination with vorasidenib, a dual inhibitor of mutant IDH1 and ID…

Low Grade Glioma of Brain

Estimated

~$10 – $7,500

Katy Peters, MD, PhDNCT05609994

Phase 2

Tryptophan-kynurenine Pathway PET Imaging in Human Gliomas

The goal of this clinical trial is to evaluate Positron emission tomography/computed tomography (PET/CT) imaging with the radiotracer 1-(2-\[18F\]fluoroethyl)-…

Low Grade GliomaGlioblastoma

Estimated

~$10 – $7,500

Barbara Ann Karmanos Cancer InstituteNCT07735819

Phase 1

A Pilot Study Evaluating the Toxicity and Clinical Benefit of Mitogen-activated Protein Kinase (MAPK) Pathway Inhibition Combined With Programmed Cell Death-1 Checkpoint Blockade (Anti-PD1) for the Treatment of BRAF-altered Pediatric Gliomas

Pediatric gliomas harboring BRAF-alterations, commonly BRAFV600 mutation or KIAA1549-BRAF fusion, are currently treated with either chemotherapy or mitogen act…

Low Grade GliomaHigh Grade Glioma

Estimated

~$10 – $6,250

Ann & Robert H Lurie Children's Hospital of ChicagoNCT06712875

Phase 2

Post-Operative Dosing of Steroids Post Craniotomy for Brain Tumor (PODS)

This phase II trial tests the effect of decreasing (tapering) doses of dexamethasone on steroid side effects in patients after surgery to remove (craniotomy) a…

Low Grade GliomaMalignant Brain GliomaMalignant Brain Neoplasm+1 more

Estimated

~$10 – $6,250

Emory UniversityNCT06132685

Phase 2

A Phase II Study of Vaccinations With HLA-A2 Restricted Glioma Antigen Peptides in Combination With Poly-ICLC for Children With Recurrent Unresectable Low-Grade Gliomas (LGG)

The study will assess the immunogenicity, safety and preliminary clinical efficacy of the glioma associated antigen (GAA)/tetanus toxoid (TT) peptide vaccine a…

Low Grade Glioma

Estimated

~$10 – $7,500

James FelkerNCT02358187

Observational

PNOC042: A Phase 2, Multi-institutional Trial, Evaluating the Efficacy of Laser Interstitial Thermal Therapy (LITT) in Children, Adolescents and Young Adults With Recurrent or Progressive Low-grade Gliomas (LGG)

This study aims to evaluate the efficacy of Laser Interstitial Thermal Therapy (LITT) in treating recurrent or progressive, low-grade gliomas (LGG) in pediatri…

Low-grade GliomaRecurrent Low Grade GliomaLow Grade Glioma of Brain+1 more

Estimated

~$10 – $5,625

University of California, San FranciscoNCT07506239