Browse Studies — Arctuva

Phase 1

Evaluation of 18F-Fluciclovine PET-MRI as a Biomarker of Response in Pediatric and Young Adult Patients With Low Grade Gliomas (LGG)

The purpose of this study is to see if 18F-Fluciclovine (Axumin®) is useful and safe in the management of children with Low Grade Gliomas (LGG). Imaging with 1…

GliomaLow-grade GliomaLow Grade Glioma of Brain+2 more

Estimated

~$10 – $6,250

Children's Hospital of PhiladelphiaNCT05555550

Phase 2

A Phase 2 De-escalation Study of Dabrafenib and Trametinib for Patients With BRAF V600 Mutant Low-Grade Gliomas

This phase II trial studies how well de-escalating the drugs dabrafenib and trametinib works in treating patients with low-grade gliomas that have a BRAF V600 …

BRAF V600 MutationLow-grade GliomaLow Grade Glioma of Brain+1 more

Estimated

~$10 – $5,625

University of California, San FranciscoNCT07110246

Phase 1

ViCToRy: Vorasidenib in Combination With Tumor Specific Peptide Vaccine for Recurrent IDH1 Mutant Lower Grade Gliomas

The purpose of this study is to determine the safety and efficacy of a PEPIDH1M vaccine in combination with vorasidenib, a dual inhibitor of mutant IDH1 and ID…

Low Grade Glioma of Brain

Estimated

~$10 – $7,500

Katy Peters, MD, PhDNCT05609994

Observational

PNOC042: A Phase 2, Multi-institutional Trial, Evaluating the Efficacy of Laser Interstitial Thermal Therapy (LITT) in Children, Adolescents and Young Adults With Recurrent or Progressive Low-grade Gliomas (LGG)

This study aims to evaluate the efficacy of Laser Interstitial Thermal Therapy (LITT) in treating recurrent or progressive, low-grade gliomas (LGG) in pediatri…

Low-grade GliomaRecurrent Low Grade GliomaLow Grade Glioma of Brain+1 more

Estimated

~$10 – $5,625

University of California, San FranciscoNCT07506239