Browse studies

Find your next paid study

31 recruiting studies matching your filters

Evaluating Conversational Artificial Intelligence for Depression Management

The goal of this clinical trial is to evaluate how a conversational method of collecting medical history affects patients' perceptions and experiences compared…

Major Depressive Disorder (MDD)

Estimated

~$10 – $6,250

George Mason UniversityNCT07105397

Phase 1

Engaging the Subgenual Cingulate With Brain Stimulation for Depression

The goal of this clinical trial is to learn how transcranial magnetic stimulation (TMS) affects brain circuits involving the subgenual anterior cingulate corte…

DepressionMajor Depressive Disorder (MDD)Depression - Major Depressive Disorder+3 more

Estimated

~$10 – $6,250

University of PennsylvaniaNCT07804459

Phase 2

A Phase 2 Double-blind, Randomised, Placebo-controlled Trial to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of DT-101 in Adults With Major Depressive Disorder Receiving Pharmacological Therapy for Depression

In this study, researchers will learn more about a study drug called DT-101 in participants with Major Depressive Disorder (MDD), a form of depression. The goa…

Major Depressive Disorder (MDD)

Estimated

~$10 – $8,750

Draig Therapeutics LtdNCT07610473

Phase 2

A Phase 2 Double-blind, Randomised, Placebo-controlled Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of DT-101 in Adults With Major Depressive Disorder (MDD)

The goal of this clinical trial is to learn if DT-101 can treat depression in adults. The effect of DT-101 will be compared to placebo. Subjects will attend th…

Major Depressive Disorder (MDD)

Estimated

~$10 – $8,750

Draig Therapeutics LtdNCT07300969

Phase 2

Targeting Neurosteroid Pathways in Alcohol Use Disorder: Clinical and Neural Impact of Pregnenolone Therapy

This study will evaluate whether pregnenolone is an effective treatment for adults with Alcohol Use Disorder (AUD) and Major Depressive Disorder (MDD). Partici…

Alcohol Use Disorder (AUD)Major Depressive Disorder (MDD)

Estimated

~$10 – $7,500

Sherwood Brown, MD, PhDNCT07734701

Observational

Safety And Efficacy of Remotely Supervised Home-Based tDCS Treatment Of Major Depressive Disorder

The REACH-tDCS study will evaluate the safety and efficacy of a noninvasive, at-home self-administered Sooma tDCS brain stimulation treatment for Major Depress…

Major Depressive Disorder (MDD)

Estimated

~$10 – $8,750

Sooma Medical IncNCT06976697

PREDICT-ACC: Prediction of REsponse to Depression Interventions (Accelerated rTMS) Using Clinical and TD-fNIRS Measurements

This observational, longitudinal, multi-cohort study aims to evaluate functional brain activity in adults undergoing treatment for Major Depressive Disorder (M…

Major Depressive Disorder (MDD)fNIRS

Dynorphin/Kappa Opioid Receptor Signaling Role in Ketamine's Anti-suicidal Ideation Effect

This study explores how stress, suicidal thoughts, and ketamine's effects are connected in people with major depressive disorder. Stress increases the risk for…

Major Depressive Disorder (MDD)

Estimated

~$10 – $7,500

New York State Psychiatric InstituteNCT07139106

Phase 1

Advancing Pregnenolone as a Novel Therapy for Co-Occurring Cannabis Use Disorder and Depression

This is UG3 phase of a multi-site, milestone-driven UG3/UH3 research program evaluating pregnenolone for individuals with co-occurring cannabis use disorder (C…

Cannabis Use DisorderMajor Depressive Disorder (MDD)

Estimated

~$10 – $6,250

University of Texas Southwestern Medical CenterNCT07685964

Observational

Mechanisms Of Orbitofrontal Stimulation in Depression (MOOD)

The orbitofrontal cortex (OFC), a region involved in emotional regulation, decision making, and reward processing, is a key area linked to antidepressant respo…

Major Depressive Disorder (MDD)

Estimated

~$10 – $7,500

Subha SubramanianNCT07230990

Computationally, Electrophysiologically, and Qualitatively Characterizing Serotonergic Psychedelics; Transdiagnostic Therapeutic and Pro-Psychotic Effects

This is an observational study which does NOT directly administer a psychedelic substance but rather recruits participants who are already participating in ano…

OCDMajor Depressive Disorder (MDD)Alcohol Use Disorder (AUD)+8 more

Estimated

~$10 – $750

Yale UniversityNCT06624137

Phase 4

Central Cholinergic Dysfunction in Depression: PET Imaging of a Novel Treatment Target With [18F]VAT to Assess the Antidepressant Effect of Nicotine

In the brain, certain nerve cells communicate using a chemical called acetylcholine. Acetylcholine is thought to be important for several functions including m…

Major Depressive Disorder (MDD)

Estimated

~$10 – $6,250

Stony Brook UniversityNCT07095205