Browse Studies — Arctuva

Phase 1

Investigational Study of Glycerol Tributyrate in MELAS and LHON-Plus

This is a parallel arm non-randomized dose-escalation, open-label basket exploratory phase 1 clinical trial where Mitochondrial encephalopathy, lactic acidosis…

MELAS SyndromeLebers Hereditory Optic Neuropathy With Extra Ocular Symptoms (LHON-Plus)

Estimated

~$150 – $3,000

Actual pay is set by the research site.

George Washington UniversityNCT06792500

Mitochondrial Encephalomyopathies and Mental Retardation: Investigations of Clinical Syndromes Associated With MtDNA Point Mutations

Carriers of the m.3242A\>G mutation often have clinical symptoms which can include migraines, seizures, strokes, hearing loss, balance issues, gastrointestinal…

MELAS or m.3243 A>G Mitochondrial DNA Mutation Carrier

Estimated

~$10 – $750

Actual pay is set by the research site.

Columbia UniversityNCT01532791

Phase 3

A Phase III, Randomised, Double-blind, Placebo-controlled, Parallel-group, Pivotal Trial to Assess the Efficacy and Safety of Sonlicromanol in Adult Subjects With a Genetically Confirmed Mitochondrial DNA tRNALeu(UUR) m.3243A>G Variant

The KHENERFIN study aims to determine whether the study medicine, sonlicromanol, is able to reduce symptoms of fatigue and the impact of fatigue on daily life,…

Mitochondrial DiseasesMaternally Inherited Diabetes and Deafness (MIDD)Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-like Episodes (MELAS)+1 more

Estimated

~$50 – $2,250

Actual pay is set by the research site.

Khondrion BVNCT06451757