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48 recruiting studies matching your filters

Continuous Glucose Monitoring in Patients Undergoing Cardiopulmonary Bypass

The purpose of this research study is to test the accuracy of the Dexcom continuous glucose monitoring device during the cardiothoracic surgical procedure and …

Glucose Metabolism Disorders (Including Diabetes Mellitus)

Estimated

~$10 – $750

Actual pay is set by the research site.

Wake Forest University Health SciencesNCT06861881

Observational

Plasma Lipids-dependent Vitamin E Metabolism During Dynamic Hyperlipidemia

Background: Obesity is known to lead to diseases such as diabetes and high cholesterol (or fats) in the blood (hyperlipidemia). But no one knows why. Research…

Lipid Metabolism Disorders

Estimated

~$10 – $675

Actual pay is set by the research site.

National Heart, Lung, and Blood Institute (NHLBI)NCT07715890

Phase 2

A Multi-gene Pharmacogenetic Panel to Prevent Adverse Drug Reactions in Daily Primary Care Practice: Open-label, Mayo Clinic Multisite (Mayo Clinic Health System-Rochester Primary Care), Controlled, Implementation Study Taking the Results of the PREPARE Study Into Minnesota (PREPARE-Mayo)

The purpose of this study is to determine whether the implementation of pre-emptive pharmacogenomic (PGx) testing of a panel of clinically relevant PGx markers…

Pharmacogenomic Drug InteractionSide Effect of DrugIneffective Drug Action+2 more

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Mayo ClinicNCT06322238

Rare and Atypical Diabetes Network

RADIANT is a network of 14 clinical sites and several laboratories dedicated to the study of atypical diabetes. The objective of this study is to define new f…

Diabetes MellitusDiabetes Mellitus ProgressionGlucose Intolerance+4 more

Estimated

~$10 – $750

Actual pay is set by the research site.

University of South FloridaNCT05544266

Phase 4

Quantitation of Hepatic Mitochondrial Fluxes in Humans With Nonalcoholic Fatty Liver Disease (NAFLD)

In this study the investigators will quantitate hepatic mitochondrial fluxes in T2D patients with NAFL and NASH before and after 16-weeks treatment with the in…

Non-Alcoholic Fatty Liver DiseaseType 2 DiabetesMitochondrial Metabolism Disorders

Estimated

~$25 – $1,000

Actual pay is set by the research site.

The University of Texas Health Science Center at San AntonioNCT05305287

Prospective Study of the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders

Background: Pyrimidine and purine metabolism disorders (DPPMs) affect how the body metabolizes chemicals called pyrimidines and purines. DPPMs can cause dysfu…

AMPD3, OMIM*102772, AMP Deaminase DeficiencyAK1, OMIM *103000, Adenylate Kinase DeficiencyAMPD1, OMIM *102770, Myopathy Due to Myoadenylate Deaminase Deficiency+25 more

Phase 1

A Phase I/IIa, Single Site, Open-Label, Ascending Dose Study to Evaluate the Safety and Efficacy of OPF-310 [Encapsulated Porcine Islet Cells for Xenotransplantation] in Subjects With Type 1 Diabetes Mellitus

This study is First In Human study for Encapsulated Porcine Islet Cells for Xenotransplantation (OPF-310). The purpose of this study to assess the safety, tole…

Diabetes Mellitus, Type 1HypoglycemiaIslet Cell Transplantation+14 more

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Imaging Oxidative Metabolism and Neurotransmitter Synthesis in the Human Brain

Investigators propose to develop hyperpolarized \[13C\]-labeled pyruvate as potential imaging probes to assess two essential in vivo processes in cerebral meta…

Brain Metabolism

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Texas Southwestern Medical CenterNCT03849963

Phase 2

Regulation of Endogenous Glucose Production by Central KATP Channels

Type 2 diabetes (T2D) affects the ability of the body to process glucose (sugar). Under fasting conditions, the liver is able to make sugar to maintain glucose…

Diabetes MellitusGlucose Metabolism Disorders

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Albert Einstein College of MedicineNCT03540758

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs) for Transplantation in Pediatric and Adult Patients With Hematologic Malignancies and Other Indications

This study is an access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs) in pediatric and adult patients with hematologic maligna…

Hematologic MalignanciesInherited Disorders of MetabolismInherited Abnormalities of Platelets+14 more

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Observational

Impact of Food Combinations on the Stimulation of Post-exercise Muscle Protein Synthesis in Healthy Adults

In the present semi-crossover randomized design, 15 recreationally active young adults (19-40 y) will receive stable isotope tracer infusions and perform a sin…

Muscle Protein Synthetic Response to ProteinMuscle Protein SynthesisMuscle Health+3 more

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Illinois at Urbana-ChampaignNCT07367854

Observational

Effects of an Amylopectin Chromium Blend on Whole-Body Protein Kinetics and Glucose Control in Peri/Post-Menopausal Women

The goal of this study is to better understand how an amylopectin chromium blend may influence whole body protein balance in women during midlife, when hormona…

Glucose Monitoring, ContinuousWhole Body Protein MetabolismPeri-menopausal Women+1 more

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Nutrition 21, Inc.NCT07402382