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28 recruiting studies matching your filters
Phase 2
Early-phase Biomarker-based Trial of NPC-1 for Alzheimer's Disease Pathology
This early phase, open label, single arm clinical trial will determine the intraindividual safety, tolerability and effects of NPC1 (parthenolide and ipriflavo…
Alzheimer DiseaseMild Cognitive Impairment (MCI)Subjective Cognitive Decline (SCD)
Massachusetts General HospitalNCT07236190
Genetic Studies of Early-onset Dementia
The aim of this study is to identify genetic factors that contribute to risk and progression of early-onset dementia (loss of memory function before the age of…
Dementia, Early OnsetAlzheimer Dementia (AD)Mild Cognitive Impairment (MCI)+1 more
Columbia UniversityNCT04906863
Assessing Tools That Predict and Stage Mild Cognitive Impairment
The goal of this observational study is to learn how well a multimodal "Progression and Risk" (PR) model can predict and stage early mild cognitive impairment …
Mild Cognitive Impairment (MCI)Alzheimer Dementia (AD)Alzheimer Disease (AD)+1 more
Prevention Research Consortium Corp.NCT07516119
Observational
Ketogenic Diet to Reduce Osteoarthritis Pain in MCI
Osteoarthritis and mild cognitive impairment are common conditions that share underlying biological processes related to metabolism and inflammation. This stud…
Osteoarthritis (OA) of the HipOsteoarthritis (OA) of the KneeOsteoarthritis (OA) of the Shoulder+5 more
University of Kansas Medical CenterNCT07417891