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125 recruiting studies matching your filters

A Phase II, Open-Label, Multicenter Study With a Safety Run-In to Evaluate the Safety, Tolerability, Efficacy, Pharmacokinetics and Pharmacodynamics of MT027 Administrated Intracerebroventricularly in Patients With Recurrent or Progressive Glioblastoma (WHO Grade 4)

This is a Phase II trial to evaluate the safety, tolerability, efficacy, and PK/ pharmacodynamic profiles of MT027 injected via ICV in participants with recurr…

Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype

Estimated

~$10 – $8,750

T-MAXIMUM Pharmaceutical IncNCT07386002

Clinical Correlation Evaluation of the LIVERFAStTM Test for Diagnosing Important Liver Lesions of Fibrosis and Steatosis Against MR-based Liver Assessment, Magnetic Resonance Elastography (MRE) for Liver Fibrosis and MR-based Assessment of Steatosis, in Adult US Population.

This is a retrospective cross-sectional research intended to explore the utility of LIVERFASt in the clinical pathways for the detection of liver fibrosis and …

Liver Fibrosis Due to NASHMASLD - Metabolic Dysfunction-Associated Steatotic Liver DiseaseAlcohol Liver Disease

Estimated

~$10 – $1,050

Fibronostics USA, IncNCT06797596

Phase 1

A Double-Blind, Active-Controlled, Multiple-Ascending Dose, Phase 1b/2a Study of Aerosolized RSP-1502 Delivered Via the PARI LC Plus® Nebulizer in Subjects With Cystic Fibrosis and Chronic Pseudomonas Aeruginosa Lung Infection

A double-blind, active-controlled, multiple-ascending dose, safety study of aerosolized RSP-1502 in subjects with cystic fibrosis Pseudomonas aeruginosa lung i…

Cystic Fibrosis LungRespiratory Infections, Recurrent, ChronicPseudomonas Aeruginosa

Estimated

~$10 – $8,750

Respirion Pharmaceuticals Pty LtdNCT06016088

Philips FAST picoSAT Convenience Sampling for Clinical Performance in Neonate, Infant, and Pediatric Patients

The main goal of this study is to look at the performance of the neonatal, infant, and pediatric Philips SpO2 sensors with the Philips FAST Pulse Oximetry tech…

SpO2Nasal Alar Collapse, BilateralOxygen+1 more

Estimated

~$10 – $750

Philips Clinical & Medical Affairs GlobalNCT06372106

Phase 1

An Open Label, Exploratory, Proof-of Concept Study of Triheptanoin as Treatment for Patients With Primary-Specific Pyruvate Dehydrogenase Complex (PDC) Deficiency

This is a medical research study to test a medication in patients with a disease called Pyruvate Dehydrogenase Complex (PDC) Deficiency. The medication is trih…

Pyruvate Dehydrogenase Complex Deficiency

Estimated

~$10 – $7,500

Jirair Krikor BedoyanNCT06340685

Phase 3

A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Long-Term Clinical Benefit of Govorestat in Patients With Charcot-Marie-Tooth-Sorbitol Dehydrogenase Deficiency (CMT-SORD)

This study is designed to assess the long-term efficacy and clinical benefit of AT-007 in patients with CMT-SORD. This randomized, double-blind study will asse…

Charcot-Marie-Tooth Disease With Sorbitol Dehydrogenase Deficiency (CMT-SORD)

Estimated

~$10 – $8,750

Applied Therapeutics, Inc.NCT07191912

Observational

Cartilage Remodeling Using Low-Temperature Radiofrequency for Facial Reconstruction

The goal of this study is to evaluate the efficacy of using the Vivaer low-temperature radio-frequency (LTRF) device to reshape ex-vivo human nasal or auricula…

Nasal Valve CollapseNose Enhancement

Estimated

~$10 – $6,250

Indiana UniversityNCT07032675

Androgens and Nonalcoholic Fatty Liver Disease (NAFLD) In Reproductive-Aged Women With and Without Polycystic Ovary Syndrome (PCOS)

The researchers want to learn how androgens, a type of sex hormone, might affect nonalcoholic fatty liver (NAFLD) in young women over time. NAFLD happens when …

PCOSNAFLDNASH

Estimated

~$10 – $675

University of California, San FranciscoNCT06124261

Phase 4

Refining Treatment Options for Trichomonas Vaginalis Infection in Women and Men: A Comparative Analysis of Oral Multi-Dose Metronidazole and Single-Dose Secnidazole

This is a multi-centered, randomized, open-label, parallel, phase IV clinical trial comparing the effectiveness and cost-effectiveness of oral multi-dose metro…

Trichomonas VaginitisBacterial Vaginitis

Estimated

~$10 – $6,250

Tulane UniversityNCT06261840

Pathobiomes in Gut of Critically Ill Patients

Despite powerful antibiotics, 50% of the intestinal tracts of critically ill surgical patients are colonized by Pseudomonas aeruginosa, whose mere presence in …

Pseudomonas Aeruginosa

Estimated

~$10 – $750

University of ChicagoNCT06822465

Phase 1

The Role of IL5 in Epithelial Cell Integrity

The goal of this laboratory study is the examine the effect of mepolizumab drug on the health and function of the cells lining the human nasal airways in vitro…

Chronic Rhinosinusitis With Nasal PolypsChronic Rhinosinusitis (Diagnosis)

Estimated

~$10 – $6,250

Johns Hopkins UniversityNCT05895929

Non-Invasive Biomarkers for Metabolic Liver Disease (NIMBLE) Study 2.0 - An FNIH Biomarkers Consortium Study

The Non-Invasive Biomarkers for Metabolic Liver Disease (NIMBLE) study is a comprehensive, multi-year collaborative effort to standardize, validate and advance…

Metabolic Associated Fatty Liver DiseaseMetabolic Associated Steatotic Liver DiseaseCirrhosis, Liver+5 more

Estimated

~$10 – $675

Foundation for the National Institutes of HealthNCT07122700