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27 recruiting studies matching your filters
Autism Word Learning and Infant Directed-Speech
The overall objective of this research is to determine whether parentese delivered in the video format (Aim 1) and in live interaction (Aim 2) facilitates nove…
Automated Assessment of Neurodevelopment in Infants at Risk for Motor Disability
Early childhood detection of motor delays or impairments provides the opportunity for early treatment which improves health outcomes. This study will use state…
Spontaneous Motor-voice Assessment in Infants Using Video and Audio Recordings.
The goal of this observational study is to discover features of normal and disordered motor-voice profiles that are biobehavioral markers of physical disabilit…
Neurogenetic Disorders: A Longitudinal Study on Natural History and Intervention Strategies
The purpose of this study is to analyze patterns in individuals with hnRNP (and other) genetic variants, including their neurological comorbidities, other medi…
A Multinational, Multicenter Study With an Open-Label Phase 1b and a Randomized, Double-Blind, Placebo-Controlled Phase 3 Followed by an Open-Label Extension to Assess the Efficacy, Safety, Tolerability, and Pharmacokinetics of Radiprodil in Participants With GRIN-Related Neurodevelopmental Disorder
The Phase 3 portion of Study RAD-GRIN-101 is a multinational, multicenter, randomized, double-blind, placebo-controlled trial followed by an open-label extensi…
Impact of the Hospital to Home: Optimizing Preterm Infant Environment (H-HOPE) Intervention on Infants With Congenital Defects Requiring Neonatal Surgery and Their Parents.
Infants born with congenital defects may require major surgery in the neonatal period. These infants are at risk for neurodevelopmental impairments. Additional…
Virtual Platforms for Genetics Evaluation in the Medically Underserved
This study aims to transform the current clinical practice paradigm by leveraging an internally designed web-based model of delivery of care called Consultagen…
Impact of Timing of Initiation of Sulphonylurea Therapy on Neurodevelopmental Outcomes in Individuals With Intermediate Developmental Delay, Epilepsy and Neonatal Diabetes (iDEND) Syndrome Due to the V59M Mutation in the KCNJ11 Gene
The goal of this observational study is to learn about the impact of the diabetes drug glibenclamide (glyburide) on neurodevelopment in individuals with iDEND …
NICU Antibiotics and Outcomes Follow-Up Study
The NANO follow-up study is designed to determine whether a simple, cost-effective intervention- withholding antibiotics at birth- reduces clinically relevant …
Electrophysiologic Sleep Phenotyping and Sleep-Dependent Neuro-maturation in Clinical and Healthy Pediatric Populations
Background: During the first few decades of life, the brain changes dramatically in shape and function. Sleep lets researchers measure these changes. Research…
School-based Paraeducator Education for Engagement at Recess
The purpose of the proposed three-site study is to test whether an educator-level implementation strategy, coaching, with or without a school-level implementat…
Fetal Cerebrovascular Autoregulation in Congenital Heart Disease and Association With Neonatal Neurobehavior
Determine 1) the impact of abnormal fetal cerebrovascular physiology with neurodevelopmental delay (ND) outcomes and 2) how this relationship is modified by pa…