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4 recruiting studies matching your filters
Phase 1
A Multicenter Phase Ib/II Study to Evaluate the Safety, Efficacy and Pharmacokinetics of NBM-BMX in Patients With Metastatic Uveal Melanoma
This study is being done to find the best dose of an investigational drug called NBM-BMX for people with metastatic uveal melanoma, a type of eye cancer that h…
Metastatic Uveal MelanomaUveal Melanoma, MetastaticUveal Melanoma, Recurrent+2 more
Novelwise Pharmaceutical CorporationNCT07136181
Phase 1
A Phase 1/2, Open-label Study of a Modified Interleukin-2 Fusion Protein (IOV-3001) in Participants With Previously Treated, Unresectable or Metastatic Melanoma Who Will Receive Lifileucel
A Phase 1/2, open-label study of a modified interleukin-2 fusion protein (IOV 3001) in participants with previously treated, unresectable or metastatic melanom…
Unresectable MelanomaMetastatic MelanomaOcular Melanoma
Iovance Biotherapeutics, Inc.NCT06940739
Phase 3
A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects With Primary Indeterminate Lesions or Small Choroidal Melanoma
The primary objective is to determine the safety and efficacy of belzupacap sarotalocan (bel-sar) compared to sham control in patients with primary indetermina…
Choroidal MelanomaIndeterminate LesionsUveal Melanoma+1 more
Aura BiosciencesNCT06007690
Phase 2
A Phase II Trial of Olaparib in Combination With Pembrolizumab for Advanced Uveal Melanoma
This is a prospective phase II multi-center trial of the combination of the PARP inhibitor olaparib with the immune checkpoint inhibitor pembrolizumab in advan…
Uveal MelanomaOcular Melanoma
H. Lee Moffitt Cancer Center and Research InstituteNCT05524935