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235 recruiting studies matching your filters

Brief Digitally-Enhanced Intervention for Managing Emotional Pain and Reducing Alcohol Use During Medication for OUD

The goal of this clinical trial is to reduce heavy drinking and enhance medication for opioid use disorder (MOUD) outcomes in individuals receiving MOUD. The m…

Opioid Use Disorder

Estimated

~$10 – $6,250

Ohio State UniversityNCT06718491

Phase 1

Cannabis Modulation of Outcomes Related to Opioid Use Disorder: Opioid Withdrawal, Abuse Potential and Safety

This study plans to enroll participants with opioid use disorder who are not currently seeking treatment to assess the effects of cannabis on opioid withdrawal…

Opioid Use Disorder

Estimated

~$10 – $7,500

Shanna Babalonis, PhDNCT05729932

Observational

Machine-Learning Prediction and Reducing Overdoses With EHR Nudges

The goal of this cluster randomized clinical trial is to test a clinician-targeted behavioral nudge intervention in the Electronic Health Record (EHR) for pati…

Opioid OverdoseOpioid UseOpioid Use Disorder+1 more

Estimated

~$10 – $6,250

University of PittsburghNCT06806163

Opioid Use Disorder and Pain

The goal of this observational study is to characterize the brain processes of pain avoidance learning dysfunctions in individuals with opioid use disorder (OU…

Opioid Use DisorderHealthy Controls Group - Age and Sex-matched

Estimated

~$10 – $750

Yale UniversityNCT06800703

Phase 4

Optimizing Evidence-based HIV Prevention Targeting People Who Inject Drugs on PrEP

The investigators will conduct an optimization trial among N=256 PWID newly started on medication for opioid use disorder and Pre-Exposure Prophylaxis (PrEP) t…

HivOpioid Use Disorder

Estimated

~$10 – $6,250

University of ConnecticutNCT05669534

Observational

Coordinating Outpatient bupreNorphiNe for Emergency Care and Continuing Treatment

The main purpose of this stepped wedge trial will be to test the impact of a bundle of implementation strategies designed to improve ED-outpatient care coordin…

Opioid Use Disorder

Estimated

~$10 – $6,250

University of California, DavisNCT07024498

Phase 4

Injectable Buprenorphine During Transition Out of Prison: A Partially Randomized Preference Pilot Trial

The goal of this pilot trial is to compare two branded extended-release buprenorphine (XR-B) formulations (Sublocade vs. Brixadi) to explore how they improve t…

Opioid Use DisorderIncarcerationMedications for Opioid Use Disorder+1 more

Low-Dose Short-Term Ketorolac to Reduce Chronic Opioid Use in Orthopaedic Polytrauma Patients

The goal of this randomized clinical trial is to learn if the use of a low-dose nonsteroidal anti-inflammatory drug (NSAID), ketorolac, reduces the rate of chr…

Orthopaedic TraumaChronic Opioid Use

Estimated

~$10 – $6,250

Massachusetts General HospitalNCT06201676

Observational

Prescribe to Prevent HIV (P2PH): Enhancing Clinic-based Prescribing of Harm Reduction: A Clinical Trial to Prevent HIV and Severe Injection-related Infections Among PWID

In the U.S., an estimated 3.6 million people who inject drugs (PWID) face a growing yet preventable health crisis, with rising cases of serious injection-relat…

People Who Use Opioids/People With Opioid Use Disorder (OUD)

Estimated

~$10 – $6,250

University of PittsburghNCT07073924

Observational

Supporting Treatment Access and Recovery in Co-Occurring Opioid Use and Mental Health Disorders

This 4-year study will randomize 1,000 people with co-occurring opioid use and mental health disorders (COD) at medication for opioid use disorder (MOUD) clini…

Opioid Use DisorderMental Health Disorder

Estimated

~$10 – $6,250

University of Massachusetts, WorcesterNCT05138614

Observational

Neurobiological Consequences of Long-Term Opioid Therapy in the Brain and Spinal Cord

The purpose of this study is to compare activity in the brains of female adults with chronic pain and/or opioid use, and healthy female adults that may help to…

Chronic PainOpioid Use

Estimated

~$10 – $6,250

Duke UniversityNCT05905419

Observational

Contingency Management to Improve Medication for Opioid Use Disorder Continuation After Discharge From the Emergency Department

Project Summary The goal of this pilot clinical trial is to assess contingency management (CM) for increasing attendance at outpatient clinics after Medication…

Opioid Use Disorder

Estimated

~$10 – $6,250

University of VermontNCT07129902