Find your next paid study

Eli Lilly and CompanyNCT05986292

Phase 2

Randomized, Placebo-Controlled, Phase 2 Clinical Trial to Evaluate LY4065967 for the Treatment of Osteoarthritis

The main purpose of this study is to test the safety and efficacy of study drug for the treatment of knee pain due to osteoarthritis (OA). This trial is part o…

Osteoarthritis, KneeChronic Pain

Eli Lilly and CompanyNCT07641517

Phase 2

Cannabinoid Interactions With Central and Peripheral Pain Mechanisms in Osteoarthritis of the Knee

This clinical trial is being done to better understand how daily treatment with Tetrahydrocannabinol (THC), Cannabidiol (CBD), or the combination of CBD plus T…

Osteoarthritis, KneeOsteoarthritis of the Knee

Steven E Harte, PhDNCT04992624

Low-dose RADIOtherapy for Knee Osteoarthritis (RADIO-KO): Protocol for a Single-center, Sham-controlled, Randomized Clinical Trial

The primary aim of this study is to investigate whether low-dose radiotherapy is an effective treatment to reduce the pain of knee osteoarthritis. A secondary …

ObesityOverweightOsteoarthritis, Knee

Mayo ClinicNCT06887829

Phase 3

Efficacy and Safety of NNC0487-0111 s.c. Once-weekly in Participants With Overweight or Obesity, and Knee Osteoarthritis (AMAZE 6)

This study is being done to look at the safety and effect of NNC0487-0111 in people with excess body weight and knee osteoarthritis when compared to placebo. T…

Novo Nordisk A/SNCT07509307

Boosting Exercise Adherence in Knee Osteoarthritis (BOOST-OA)

This project, conducted within the Department of Veterans Affairs Healthcare System (VHA), will test the effectiveness of an intervention to improve adherence …

VA Office of Research and DevelopmentNCT07219732

~$10 – $5,625

The Osteoarthritis Prevention Study

The goal of this study is to establish the efficacy of an intervention of dietary weight loss, exercise, and weight-loss maintenance for knee Osteoarthritis (O…

Wake Forest UniversityNCT05946044

Evaluation of the MISHA® Knee System for Symptom Relief in Subjects With Medial Knee Osteoarthritis Versus the Use of Non-surgical Treatment: Randomized Clinical Trial and Comparison of Therapies for Medial Knee Osteoarthritis

Prospective, multicenter, two-arm, 2:1 randomized controlled trial (RCT) comparing the benefits in subjects with medial knee osteoarthritis who are treated wit…

Effects of Haptic Movement Retraining on Osteoarthritis Progression

This study investigates how well individuals with knee osteoarthritis can learn to alter their calf muscle activation using haptic biofeedback while walking an…

Stanford UniversityNCT06208631

Phase 4

RCT to Evaluate the Effects of Zilretta (Triamcinolone Acetonide- Extended Release) and Kenalog (Triamcinolone Acetonide- Immediate Release) on Blood Glucose in Subjects With Osteoarthritis of the Knee and Type 2 Diabetes Mellitus

A Phase 2 Randomized Study to Evaluate the Effects of triamcinolone acetonide extended-release (TA-ER; Zilretta) vs. triamcinolone acetonide immediate-release …

Osteoarthritis, KneeDiabetes Mellitus, Type 2

University of Kansas Medical CenterNCT06478186

Using Mobile Technology to Extract Mechanical Markers of Joint Health and Function in Early Knee Osteoarthritis

Veterans face a high prevalence of knee osteoarthritis (OA), but current diagnostic methods often miss early stages when interventions are more effective. This…

VA Office of Research and DevelopmentNCT07580222

~$10 – $675

Phase 4

A Randomized Controlled Trial of ZYNRELEF Versus Standard of Care for Pain Management Following Unilateral Total Knee Arthroplasty

The goal of this randomized controlled trial is to compare opioid medication consumption after surgery for patients who have a total knee replacement. The mai…

Post Operative PainOsteoarthritis, Knee