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223 recruiting studies matching your filters

Assessing the Impact of Scalp Cooling in With Metastatic Breast Cancer

This research is being done to compare rates of hair loss of people with metastatic breast who use scalp cooling versus those who do not use scalp cooling afte…

Metastatic Breast CancerChemotherapy-induced Alopecia

Estimated

~$10 – $7,500

Dana-Farber Cancer InstituteNCT04986579

Phase 1

Immunotherapy for Malignant Pediatric Brain Tumors Employing Adoptive Cellular Therapy (IMPACT)

This is an open-label phase 1 safety and feasibility study that will employ multi-tumor antigen specific cytotoxic T lymphocytes (TSA-T) directed against prote…

Medulloblastoma, ChildhoodAtypical Teratoid/Rhabdoid Tumor of CNSEmbryonal Tumor With Multilayered Rosettes+3 more

Estimated

~$10 – $5,625

Children's National Research InstituteNCT06193759

Familial Investigations of Childhood Cancer Predisposition

NOTE: This is a research study and is not meant to be a substitute for clinical genetic testing. Families may never receive results from the study or may recei…

Acute LeukemiaAdenomatous PolyposisAdrenocortical Carcinoma+43 more

Estimated

~$10 – $750

Phase 1

A Phase I, Multicenter, Open-Label, Dose-Escalation and Expansion, Safety, Pharmacokinetic, Pharmacodynamic, and Clinical Activity Study of Orally Administered AG-120 in Subjects With Advanced Hematologic Malignancies With an IDH1 Mutation

The purpose of this Phase I, multicenter study is to evaluate the safety, pharmacokinetics, pharmacodynamics and clinical activity of AG-120 in advanced hemato…

Relapsed or Refractory Acute Myeloid Leukemia (AML)Untreated AMLOther IDH1-mutated Positive Hematologic Malignancies+1 more

Estimated

~$10 – $7,500

Institut de Recherches Internationales ServierNCT02074839

Observational

Light Therapy for Chemotherapy Induced Peripheral Neuropathy in Childhood Cancer Survivors

The purpose of this study is to determine feasibility and acceptability of a six-week at-home light therapy protocol in childhood cancer survivors, to identify…

CancerChildhood CancerChemotherapy-induced Peripheral Neuropathy

Estimated

~$10 – $6,250

Yale UniversityNCT07019259

Phase 1

A Phase 1/2a Study to Assess Safety, Tolerability, and Efficacy of [212Pb]Pb-DOTAM-MAM279 in Patients With Small Cell Lung Cancer and Other DLL3 Expressing Solid Tumors

The purpose of this study is to evaluate the safety, tolerability, dosimetry and preliminary efficacy of \[212Pb\]Pb-MP0712, in patients aged ≥18 years with Sm…

Large Cell Neuroendocrine CarcinomaLarge Cell Pulmonary Neuroendocrine Carcinoma of the Lung (LCNEC)Extrapulmonary Neuroendocrine Carcinoma (EP-NEC)+4 more

Estimated

~$10 – $8,750

Molecular Partners AGNCT07278479

Phase 1

Central Nervous System Uptake of Anti-CD8+ T Cell Minibodies in Multiple Sclerosis and Progressive Multifocal Leukoencephalopathy: A Pilot Study

Background: Multiple sclerosis (MS) and progressive multifocal leukoencephalopathy (PML) are disorders that affect the central nervous system (CNS). The CNS i…

Progressive Multifocal LeukoencephalopathyMultiple SclerosisOther Neuroinflammatory Diseases With BBB Leakage

Estimated

~$10 – $5,625

National Institute of Neurological Disorders and Stroke (NINDS)NCT05849467

Phase 2

A Randomized, Double-Blind, Placebo Controlled, Multicenter Study With Optional Open-Label Extension to Evaluate the Efficacy and Safety Study of Halneuron in the Treatment of Chemotherapy-Induced Neuropathic Pain

A randomized study to determine safety and efficacy of a series of subcutaneous (SC) injections of HAL in patients with CINP, compared to matching placebo inje…

Chemotherapy Induced Neuropathic PainChemotherapy Induced Pain NeuropathyChemotherapy Induced Pain

Estimated

~$10 – $8,750

Dogwood Therapeutics Inc.NCT06848348

Pilot Study of a Novel Patient Position Monitoring System for Beam Gated Radiation Therapy of Malignancies of the Chest and Upper Abdomen

This study will evaluate the feasibility of using this novel patient position monitoring system for patients receiving radiation therapy to targets involving t…

RadiotherapyRadiotherapy, Image-Guided

Estimated

~$10 – $750

Washington University School of MedicineNCT07373496

Observational

Preventing School Exclusion and Opioid Misuse: Effectiveness of the Inclusive Skill-building Learning Approach (ISLA)

This project will test the effectiveness of the Inclusive Skill-building Learning Approach (ISLA) in reducing the use of exclusionary discipline, improving tea…

Middle SchoolsSchool ExclusionSchool Community+2 more

Estimated

~$10 – $6,250

University of OregonNCT06292078

Phase 1

A Phase 1/2 Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions

This is a Phase 1/2, multi-center, open-label basket study designed to evaluate the safety and anti-tumor activity of IDE196 in patients with solid tumors harb…

Metastatic Uveal MelanomaCutaneous MelanomaColorectal Cancer+1 more

Estimated

~$10 – $8,750

IDEAYA BiosciencesNCT03947385

Phase 1

Ruxolitinib in Combination With Chemotherapy for Untreated Nodal T-Follicular Helper (TFH) Cell Lymphomas

This phase I trial tests the safety, side effects and best dose of ruxolitinib in combination with cyclophosphamide, doxorubicin, vincristine, prednisone (CHOP…

Follicular Helper T-Cell LymphomaFollicular Helper T-Cell Lymphoma, Angioimmunoblastic-TypeFollicular Helper T-Cell Lymphoma, Follicular-Type+3 more

Estimated

~$10 – $6,250

City of Hope Medical CenterNCT07278856