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18 recruiting studies matching your filters

A Phase 2, Randomized, Placebo-Controlled Study to Assess the Safety, Tolerability, Pharmacokinetics, and Efficacy of Olatorepatide, a GLP-1/GIP Receptor Agonist, With Different Doses and Drug-Titration Algorithms in Participants Living With Overweight or Obesity

This study will test an experimental drug called olatorepatide ("study drug") to determine how safe and effective this drug is compared to placebo and how easi…

Overweight or Obesity

Estimated

~$10 – $8,750

Regeneron PharmaceuticalsNCT07685808

Phase 1

A Phase 1, Randomized, Double-Blind, Placebo-Controlled Study of the Safety, Tolerability, and Pharmacokinetics of Single Ascending Doses of REGN20934 in Adult Participants With Overweight or Obesity

This study will test a study drug called REGN20934 to see how safe and well tolerated this drug is, as well as how the drug is processed in the body for partic…

Overweight or Obesity

Estimated

~$10 – $8,750

Regeneron PharmaceuticalsNCT07594093

Phase 3

A Master Protocol for Phase 3 Randomized, Double-Blind, Placebo-Controlled Studies to Investigate the Efficacy and Safety of Once Weekly Eloralintide in Adult Participants With Osteoarthritis Knee Pain, and Obesity or Overweight (ENLIGHTEN-4)

The YDAN master protocol will support two independent studies, J3R-MC-YOA1 and J3R-MC-YOA2. Each study will investigate how well and safely Eloralintide (LY384…

OsteoarthritisOverweight or Obesity

Estimated

~$10 – $7,500

Eli Lilly and CompanyNCT07353931

Phase 4

A Phase 4, Prospective, Open-Label, Single Arm Study to Assess the Effectiveness of Tirzepatide After Initiation of Ixekizumab in Adult Participants With Moderate-to-Severe Plaque Psoriasis and Obesity or Overweight in Clinical Practice

The main purpose of this study is to assess the effectiveness of adding tirzepatide to ixekizumab therapy in standard clinical practice in participants with mo…

PsoriasisOverweight or Obesity

Estimated

~$10 – $7,500

Eli Lilly and CompanyNCT06857942

Phase 2

Taxi ROADmAP (Realizing Optimization Around Diet And Physical Activity)

The researchers will conduct 'Taxi ROADmAP (Realizing Optimization Around Diet And Physical activity)', which also utilizes MOST, and the same 4 obesity interv…

OverweightOverweight and ObesityOverweight or Obesity+2 more

Estimated

~$10 – $6,250

Memorial Sloan Kettering Cancer CenterNCT05770570

Observational

Testing Just-in-Time Adaptive Interventions (JITAIs) to Prevent Goal Disengagement in Response to Weight Regain

This trial will test the effectiveness of a weight loss maintenance intervention designed to help participants respond more adaptively to weight regain. Partic…

Overweight or Obesity

Estimated

~$10 – $7,500

ORI Community and Evaluation ServicesNCT07708064

Observational

A Randomized Control Trial to Improve Metabolic Outcomes in African American Pregnant Women

The purpose of this randomized controlled trial is to establish the effectiveness of a culturally targeted and individually tailored behavioral intervention to…

Overweight or ObesityPregnancy RelatedSleep Disturbances+9 more

Estimated

~$10 – $6,250

University of Illinois at ChicagoNCT05234125

Observational

Effect of the Thrive AI Health App on Lifestyle Behaviors and Quality of Life

The goals of this randomized trial is to learn: 1. If the Thrive AI Health app will help adults improve their everyday habits (diet, exercise, and sleep). 2. …

Diabetes Type 2Overweight or Obesity

Estimated

~$10 – $6,250

Yale UniversityNCT07376655

Observational

Timing (AM v PM) of Acute Resistance Exercise on Glycemic Control in Older Adults: The Acute T-Rex Study

The primary aim of this study is to evaluate if a single bout of AM vs PM resistance exercise has different effects on insulin sensitivity and sleep. A randomi…

Diabetes Mellitus, Type 2Insulin ResistanceGlucose Intolerance+3 more

Estimated

~$10 – $6,250

University of UtahNCT06366399

Observational

Using Real-Time Data Capture to Examine Affective Mechanisms as Mediators of Physical Activity Adherence in Interventions

This early-phase trial will test intervention strategies to influence affective mechanisms underlying physical activity and determine whether changes in those …

Physical InactivityOverweight or ObesityCancer

Estimated

~$10 – $6,250

University of Southern CaliforniaNCT06570642

Observational

Connectome-based Neurofeedback of the Craving Network to Reduce Food Cue Reactivity

This project tests whether individuals with overweight or obesity and high craving can learn to change their brain response to food cues using neurofeedback, t…

Overweight or Obesity

Estimated

~$10 – $6,250

Yale UniversityNCT06426693

Using Real-Time Data Capture to Examine Implicit Attitudes as Mediators of Physical Activity Adherence in Interventions

This early-phase trial will test intervention strategies to influence implicit attitudes towards physical activity and determine whether changes in those mecha…

Physical ActivityOverweight or ObesityCancer

Estimated

~$10 – $750

University of Southern CaliforniaNCT07044570