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193 recruiting studies matching your filters

Exploring the Biological Basis for Exercise Neuroprotection in Parkinson's Disease

The purpose of this study is to explore the relationships of exercise on inflammation in the body of older adults and people with Parkinson's disease (PD). Thi…

Parkinson Disease

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Nevada, Las VegasNCT05854524

Observational

Using Behavioral Economics and Implementation Science to Advance the Use of Genomic Medicine Utilizing an EHR Infrastructure Across a Diverse Health System

Given the expansion of indications for genetic testing and our understanding of conditions for which the results change medical management, it is imperative to…

Genetic PredispositionParagangliomaPheochromocytoma+7 more

Estimated

~$10 – $750

Actual pay is set by the research site.

University of PennsylvaniaNCT06377033

Observational

Intracranial Recordings to Characterize Action Regulation Mechanisms

Humans can rapidly regulate actions according to evolving environmental demands, however, impairments of action regulation have been identified across a number…

Parkinson Disease

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Texas Southwestern Medical CenterNCT06671626

Observational

A Pilot Study of Acute Intermittent Hypercapnia-Based Interventions on Upper Airway and Axial Motor Function in Parkinson's Disease

Parkinsonism impairs upper airway and axial motor control, leading to disordered breathing, reduced speech volume, and ineffective cough. Symptoms are poorly a…

Parkinson DiseaseParkinsonism

Estimated

~$10 – $750

Actual pay is set by the research site.

University of FloridaNCT07674264

Observational

Behavioral Intervention for Lifestyle Physical Activity in Parkinson's Disease

The investigators propose a Stage-I randomized controlled trial (RCT) of a remotely-delivered, 16-week social-cognitive theory-based behavioral intervention fo…

Parkinson Disease (PD)

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Illinois at ChicagoNCT06603012

Phase 1

A Phase 1/2 Study to Evaluate Safety, PK and Biodistribution of an Imaging Agent, 18F-OP-801, After Intravenous Administration to Patients With ALS, Alzheimer's Disease, Multiple Sclerosis, Parkinson's Disease and Healthy Volunteers

This is a Phase 1/2 study to evaluate the safety and tolerability of 18F-OP-801 in subjects with ALS, AD, MS, PD and age-matched HVs. 18F-OP-801 is intended as…

Amyotrophic Lateral Sclerosis (ALS)Parkinson Disease (PD)Alzheimer Disease (AD)+1 more

Estimated

~$500 – $10,500

Actual pay is set by the research site.

Ashvattha Therapeutics, Inc.NCT05395624

Phase 4

BOOST-PD - Better On-time Observations of Motor Fluctuations Using Wearable Sensor Technology: A Naturalistic Study on IPX-203 for Parkinson's Disease

The purpose of this study is to evaluate the effect of IPX203 (Crexont®) - the newest extended-release levodopa formulation - on the duration and quality of go…

Parkinson Disease

Estimated

~$25 – $1,000

Actual pay is set by the research site.

The Cleveland ClinicNCT07138560

Observational

TURN-IT FOG: A Novel Intervention to Improve Turning in People With PD and Freezing of Gait

The goals of this clinical trial are to 1) learn how two different rehabilitation interventions for PD can reduce Freezing of Gait (FOG) in people with Parkins…

Parkinson DiseaseFreezing of Gait Symptoms in Parkinson Disease

Estimated

~$10 – $750

Actual pay is set by the research site.

Oregon Health and Science UniversityNCT06815302

Phase 1

A Randomized, Placebo-Controlled, Single Ascending Dose (SAD) Study to Assess the Safety, Tolerability, and Pharmacokinetics of SER-252 in Patients With Parkinson's Disease and Motor Fluctuations

This is a randomized, placebo-controlled, single ascending dose (SAD) study of SER-252 in participants with Parkinson's Disease (PD) and motor fluctuations.

PARKINSON DISEASE (Disorder)Advanced Parkinson's Disease

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Serina TherapeuticsNCT07422675

Observational

Effects of Blood Pressure on Cognition and Cerebral Blood Flow in Parkinson Disease

Parkinson's disease (PD) is the second most common neurodegenerative disorder worldwide. Besides causing symptoms that impair movement, PD also causes non-moto…

Parkinson DiseaseOrthostatic HypotensionDysautonomia

Estimated

~$10 – $750

Actual pay is set by the research site.

University of California, San DiegoNCT05400174

Phase 2

An Open-Label, Exploratory, Phase 2 Scintigraphy Study Evaluating 18F-mFBG for Imaging Myocardial Sympathetic Innervation in Subjects With and Without Lewy Body Diseases

This is a Phase 2 study evaluating the positron-emitting radiopharmaceutical 18F-mFBG as an imaging agent for quantification of the effect of neurodegenerative…

Parkinson Disease (PD)Lewy Body Dementia (LBD)

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Innervate Radiopharmaceuticals LLC (Formerly: Illumina Radiopharmaceuticals LLC)NCT07176286

Observational

Characterizing Dance-related Physical Activity Behaviors Among Adults Living With Parkinson's Disease for Automated Analyses of Energy Expenditure

The first purpose of the study is to develop and test new methods for quantifying dance among adults with a diagnosis of Parkinson's using various kinds of cam…

Parkinson Disease

Estimated

~$10 – $750

Actual pay is set by the research site.

Northeastern UniversityNCT06425731