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Genetics and Aerobic Exercise to Slow Parkinson's Disease (GEARS) Trial
The proposed multi-site, Genetics and Aerobic Exercise to Slow PD (GEARS) Trial will, for the first time, determine the interplay between genetics and exercise…
Reducing Falls With Varenicline in Hypocholinergic Parkinson Disease
This trial aims to test whether one year of Varenicline, when compared to placebo, can reduce fall risk and show improvement in the ability to multitask while …
Light Therapy Intervention in Individuals With Parkinson's Disease
The study looks to investigate the effects that light therapy delivered to the frontal cortex could have on Parkinson's disease related symptoms ( both cogniti…
A Randomized, Placebo-Controlled, Single Ascending Dose (SAD) Study to Assess the Safety, Tolerability, and Pharmacokinetics of SER-252 in Patients With Parkinson's Disease and Motor Fluctuations
This is a randomized, placebo-controlled, single ascending dose (SAD) study of SER-252 in participants with Parkinson's Disease (PD) and motor fluctuations.
Using taVNS to Modulate Cardiovascular Function in Individuals With Neurologic Disease
The purpose of this study is to find out whether a type of gentle nerve stimulation, called transcutaneous auricular Vagus Nerve Stimulation (taVNS), can help …
Social Behaviors and Quality of Life in Individuals With Parkinson's Disease
Adults with Parkinson's Disease experience an array of challenges and changes in daily living, behaviors, and functioning throughout the progression of their c…
Deep Brain Stimulation Neural Recordings of Varied Stimulation During Sleep in Parkinson's Disease - The DREAMS-PD Study
This study employs an exploratory, prospective, single center, naturalistic clinical trial design with a randomized crossover intervention.
Changes in Motor Function, Quality of Life, Cardiorespiratory Fitness, and Physiological Markers in People With Parkinson's Disease Following Different Exercise Interventions.
Parkinson's disease (PD) is a progressive neurological condition that can affect movement, balance, endurance, and overall quality of life. Exercise is widely …
Vibrotactile Coordinated Reset in Parkinson's Disease - Proof of Concept Study
The purpose of our study is to evaluate Vibrotactile Coordinated Reset stimulation (vCR) and its effects on Parkinson's symptoms. vCR will be administered with…
Clinical Trial Evaluating the Efficacy and Safety of AGB101 for Treatment of Parkinson's Disease Related Psychosis
This clinical trial will test whether AGB101 (low-dose levetiracetam, 220 mg, extended release tablet) can improve symptoms of psychosis in Parkinson's disease…
Gait Pattern Analysis in Neurological Disease
The purpose of this study is to investigate whether speed-dependent measures of gait can be identified in patients with neurological conditions that affect gai…
Neurophysiology of Reward Signaling in Parkinson's Disease
The goal of this study is to learn more about the brain activity underlying Parkinson's disease risk taking and reward seeking behaviors. The investigators wil…