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Vasodilatory Effects of Light on Peripheral Artery Disease
Subjects with a known diagnosis of peripheral artery disease as measured by an abnormal ankle brachial index (\<.9 or \>1.1) will undergo a single 5 min exposu…
BEETroot Juice to Reverse Functional Impairment in PAD: The BEET PAD Trial
The BEET PAD Trial is a multi-centered double-blind randomized clinical trial designed to determine whether beetroot juice, compared to placebo, improves six-m…
The Effects of Diet and Exercise Interventions in Peripheral Artery Disease
This study is a 3-month, prospective, randomized controlled clinical trial designed to address the efficacy of the DASH dietary program combined with a home-ba…
Vascular Lab Resource (VLR) Biorepository Study
This is a study of biomarkers obtained from prospectively collected subject samples and their correlation with cardiovascular and metabolic diseases. The purpo…
Enhanced Home-Based Exercise Therapy for Peripheral Arterial Disease Through Mobile Health and Remote Monitoring
Peripheral artery disease (PAD) is a highly prevalent condition affecting up to 10% of Veterans that leads to loss of walking ability and increased risk of amp…
Oxygen-guided Supervised Exercise Therapy in Peripheral Artery Disease
Peripheral artery disease (PAD) is a cardiovascular disease manifesting from systemic atherosclerosis, which blocks the leg arteries and results in insufficien…
To Stretch, Not Strain: Impact of Passive Stretching on Calf Muscle and Gait Mechanics in PAD
The goal of this clinical trial is to assess the effects of passive calf muscle stretching in patients diagnosed with peripheral artery disease (PAD). The main…
Radiotracer Imaging of Skeletal Muscle Perfusion in Patients With Peripheral Artery Disease
The aim of this clinical study is to 1) establish a healthy database for nuclear perfusion imaging of the lower extremities and 2) assess the prognostic value …
Leg Heat Therapy to Improve Functional Performance in Peripheral Artery Disease
The goal of this randomized, double-blind, sham-controlled clinical trial is to evaluate the benefits of home-based, leg heat therapy (HT) on lower-extremity f…
IMProving Mobility After revasCularizaTion in Peripheral Artery Disease: The IMPACT PAD Trial
Lower extremity revascularization combined with supervised exercise significantly improves walking performance compared to revascularization alone in people wh…
Leg Exercise Assistive Paddling (LEAP) Therapy for Peripheral Artery Disease
The purpose of this study is to test the effects of leg exercise assistive paddling (LEAP) therapy during prolonged sitting (PS) on vascular and functional per…
Pulse Arrival Time as an Alternative Biomarker to Detect Lower-Extremity Peripheral Artery Disease
1\) The purpose of this study is to assess segmental pulse arrival time (PAT) as an alternative biomarker to detect lower-extremity peripheral artery disease (…