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41 recruiting studies matching your filters

Methadone to Reduce Chronic Opioid Use After Major Spine Surgery: The MEND Pilot Feasibility Study

The investigators propose a randomized, triple-blinded (patients, investigators, outcomes assessors), placebo-controlled pilot feasibility trial (Methadone to …

Post Operative PainSpinal Surgery

Estimated

~$25 – $1,000

Actual pay is set by the research site.

The Cleveland ClinicNCT07222072

Phase 4

Influence of Lidocaine Infusion on Motor Evoked Potential Thresholds; a Single-center, Double-blinded, Randomized Trial for Patients Undergoing Spin Surgery With Intraoperative Neurophysiologic Monitoring.

The purpose of this study is to determine the effect of lidocaine infusion on intraoperative neuromonitoring in patients undergoing spine surgery.

Spinal DiseaseAnesthesiaPost Operative Pain

Estimated

~$25 – $1,000

Actual pay is set by the research site.

Dartmouth-Hitchcock Medical CenterNCT06792474

Phase 3

A Multicenter, Double-blind, Randomized, Parallel Group, Active-controlled, Dose-ranging Study to Assess Efficacy, Safety, and Pharmacokinetics of Combogesic® 325 in Adolescent Patients (Aged 12 to Less Than 18 Years) With Moderate to Severe Postoperative Pain Associated With Orthopedic Surgery

Combogesic® 325 contains a combination of ibuprofen and acetaminophen. The purpose of this study is to compare the pain relief effects of Combogesic® 325mg and…

Post Operative Pain, Acute

Estimated

~$50 – $2,100

Actual pay is set by the research site.

AFT Pharmaceuticals, Ltd.NCT07225140

Observational

Effects of Assisted Robotic vs Laparoscopic Sleeve Gastrectomy (EARLY): A Randomized Controlled Trial on Early Postoperative Pain

This will be a prospective, obesity-registry based, single-blind randomized controlled trial with a 1:1 allocation ratio. Specific inclusion criteria are all p…

Post Operative PainLaparoscopic Sleeve GastrectomyRobotic Sleeve Gastrectomy+3 more

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Ricard CorcellesNCT06425016

Phase 3

Reduction of Post-op Pain and Opioid Consumption With the Addition of Methadone in Total Hip Arthroplasty: a Double-blind Randomized Control Trial

This randomized, double-blind controlled trial investigates whether intraoperative intravenous methadone (0.15 mg/kg based on ideal body weight) reduces acute …

Post Operative PainTotal Hip Arthroplasty

Estimated

~$50 – $1,500

Actual pay is set by the research site.

Medical University of South CarolinaNCT07227064

Observational

Effects of Transcutaneous Vagal Nerve Stimulation on Post-Surgical Return to Consciousness, Delirium, and Depression

This study will examine whether noninvasive, transcutaneous vagal nerve stimulation (tcVNS) can help restore consciousness in patients in the operating room an…

Post Operative DeliriumCognitive ImpairmentVagus Nerve Stimulation+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Northwestern UniversityNCT07610655

Phase 1

A Phase 1 Randomized, Placebo-Controlled, Blinded Study Evaluating the Safety, Tolerability, and Pharmacokinetics of ARC-001 in Participants Undergoing Third Molar Extraction

The study will test the investigational product gel against placebo (which contains no active ingredient) to determine if it is safe after wisdom tooth extract…

Acute Post Operative PainThird Molar Extraction Surgery

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Arcato Laboratories, Inc.NCT06864884

Observational

EnCompass Clamp and the AtriClip in Box Lesion and Left Atrial Appendage EXclusion Procedure for the Prevention of New Onset of Atrial Fibrillation

Post Operative Atrial Fibrillation (POAF) is the most common complication of cardiac surgery. POAF incidence can exceed 50% depending on the patient baseline c…

Post Operative Atrial FibrillationAtrial Fibrillation, Postoperative

Estimated

~$10 – $1,050

Actual pay is set by the research site.

AtriCure, Inc.NCT06989775

Phase 1

Safety and Feasibility of a Self-Balancing Exoskeleton for Rehabilitation in the Thoracic Surgical Intensive Care Unit: a Pilot Trial

Patients admitted to the Intensive Care Unit (ICU) after thoracic surgery often experience complications related to immobility, such as muscle weakness, pulmon…

Critical IllnessPost Operative ComplicationThoracic Surgery

Estimated

~$150 – $4,500

Actual pay is set by the research site.

WandercraftNCT07220733

Phase 2

Postoperative Tizanidine Use in Pelvic Reconstructive Surgery: A Pilot Study

The goal of this clinical trial is to evaluate whether adding tizanidine to the standard postoperative pain regimen improves recovery after pelvic reconstructi…

Post OperativePost Operative AnalgesiaUrogynecologic Surgery

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Hartford HospitalNCT07766837

Phase 4

Balancing Comfort and Success: Post-retrieval Ketorolac in Fresh Embryo Transfers

Ketorolac is a medication often used to relieve pain after surgery. In the past, infertility doctors have been cautious about using ketorolac after egg retriev…

Infertility (IVF Patients)Infertility TreatmentPost-op Pain+2 more

Estimated

~$25 – $1,500

Actual pay is set by the research site.

Jessica D. KresowikNCT07185724

Impact of Patient Phenotypic Features on the Experience and Effectiveness of Regional Anesthesia and Postoperative Pain

The goal of this observational study is to learn about how regional anesthesia (numbing medication) affects pain in patients with different psychosocial phenot…

Acute PainChronic Post Operative PainOpioid Use

Estimated

~$10 – $750

Actual pay is set by the research site.

Brigham and Women's HospitalNCT06466941