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16 recruiting studies matching your filters

A Randomized Trial of Neratinib, A Pan-ERBB Inhibitor, Alone or in Combination With Palbociclib, a CDK4/6 Inhibitor, in Patients With HER2+ Gynecologic Cancers and Other Solid Tumors: A ComboMATCH Treatment Trial

This phase II ComboMATCH treatment trial compares the effect of neratinib to the combination of neratinib and palbociclib in treating patients with HER2 positi…

Malignant Female Reproductive System NeoplasmMalignant Solid NeoplasmRecurrent Malignant Female Reproductive System Neoplasm+1 more

Estimated

~$10 – $5,625

National Cancer Institute (NCI)NCT06126276

Phase 2

Molecular Analysis for Combination Therapy Choice (ComboMATCH)

This ComboMATCH patient screening trial is the gateway to a coordinated set of clinical trials to study cancer treatment directed by genetic testing. Patients …

Advanced Malignant Solid NeoplasmAnatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8+12 more

Estimated

~$10 – $5,625

National Cancer Institute (NCI)

Observational

Parenting Support Intervention for Families Coping With an Advanced Cancer Diagnosis

This clinical trial examines the acceptability and effect of a parenting support intervention for families coping with solid tumor that has spread to other pla…

Metastatic Malignant Solid NeoplasmRecurrent Malignant Solid Neoplasm

Estimated

~$10 – $6,250

M.D. Anderson Cancer CenterNCT05059678

Phase 1

Modular Phase 1B Hypothesis-Testing, Biomarker-Driven, Talazoparib Combination Trial (TalaCom)

This phase Ib trial is to find out the best dose, possible benefits and/or side effects of talazoparib when given in combination with palbociclib, axitinib, or…

Advanced Malignant Solid NeoplasmMetastatic Malignant Solid NeoplasmRecurrent Malignant Solid Neoplasm

Estimated

~$10 – $6,250

M.D. Anderson Cancer CenterNCT04693468

Phase 1

A Phase 1/2 Trial of CBL0137 (NSC# 825802) in Patients With Relapsed or Refractory Solid Tumors Including CNS Tumors and Lymphoma

This phase I/II trial evaluates the best dose, side effects and possible benefit of CBL0137 in treating patients with solid tumors, including central nervous s…

Diffuse Midline Glioma, H3 K27-AlteredMetastatic Malignant Neoplasm in the Central Nervous SystemRecurrent Diffuse Intrinsic Pontine Glioma+7 more

Estimated

~$10 – $7,500

Children's Oncology GroupNCT04870944

Phase 1

A Phase 1/2 Study of Tegavivint (NSC#826393) in Children, Adolescents, and Young Adults With Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

This phase I/II trial evaluates the highest safe dose, side effects, and possible benefits of tegavivint in treating patients with solid tumors that has come b…

Colorectal CarcinomaEndometrial CarcinomaMelanoma+19 more

Estimated

~$10 – $7,500

The Adoption of Audio Recording in the Outpatient Supportive Care Center

This study evaluates how patients feel about having an audio recording of their visit to help remember information given to them and share that information wit…

Advanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell NeoplasmLocally Advanced Malignant Solid Neoplasm+2 more

Estimated

~$10 – $750

M.D. Anderson Cancer CenterNCT04871477

Phase 1

A Phase Ib/II Study of Axatilimab in Combination With Retifanlimab and Paclitaxel for the Treatment of Patients With Advanced Solid Tumors

This phase I/II trial tests the safety, side effects, and effectiveness of axatilimab in combination with retifanlimab and paclitaxel for the treatment of pati…

Advanced Malignant Solid NeoplasmMetastatic Malignant Solid NeoplasmRecurrent Malignant Solid Neoplasm+1 more

Estimated

~$10 – $7,500

OHSU Knight Cancer InstituteNCT06320405

Phase 1

A Randomized Phase I/II Study of Talazoparib or Temozolomide in Combination With Onivyde in Children With Recurrent Solid Malignancies and Ewing Sarcoma

The phase I portion of this study is designed for children or adolescents and young adults (AYA) with a diagnosis of a solid tumor that has recurred (come back…

Recurrent Solid TumorRecurrent Ewing SarcomaRecurrent Hepatoblastoma+19 more

Estimated

~$10 – $6,250

Phase 1

A Phase I Study to Investigate the Safety of the Ubiquitin Activating Enzyme Inhibitor TAK-243 in Adult Solid Tumor and Lymphoma Patients

This phase I trial studies the side effects and best dose of ubiquitin-activating enzyme (UAE) inhibitor TAK-243 (TAK-243) in treating patients with a solid tu…

Advanced LymphomaAdvanced Malignant Solid NeoplasmIndolent Non-Hodgkin Lymphoma+3 more

Estimated

~$10 – $5,625

National Cancer Institute (NCI)NCT06223542

Clonal Hematopoiesis and Therapy-Emergent Myeloid Neoplasms in Patients With Cancers (CHANCES)

This study is being done to investigate clonal hematopoiesis and therapy-emergent myeloid neoplasms in patients with ovarian or other solid cancers. Researcher…

Recurrent Fallopian Tube CarcinomaRecurrent Ovarian CarcinomaRecurrent Primary Peritoneal Carcinoma+7 more

Estimated

~$10 – $750

University of WashingtonNCT06295965

Observational Basket Trial to Collect Tissue to Develop and Train a Live Tumor Diagnostic Platform

This study is being done to collect tissue samples to test how accurately a tumor response platform, Elephas, can predict clinical response across multiple typ…

Early Stage Triple-Negative Breast CarcinomaMetastatic Bladder Urothelial CarcinomaMetastatic Cervical Carcinoma+24 more

Estimated

~$10 – $750