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Observational
A Prospective Decentralized Investigation of the Effect of a Cough Management Feature Inside a Wellness Application (CoughPro) in Refractory or Unexplained Chronic Cough (RCC/UCC)
The goal of this single-cohort clinical trial is to learn whether a smartphone-based Cough Management (CM) program can reduce cough frequency and burden in adu…
Refractory Chronic CoughUnexplained Chronic CoughCough Hypersensitivity
Hyfe IncNCT07070895
Phase 2
A Randomized, Double-blind, Placebo-controlled, Dose-escalation Study Evaluating the Efficacy of Two Doses of Duloxetine & Amitriptyline in Subjects With Refractory Chronic Cough
This research study is evaluating the effectiveness of escalating doses of Amitriptyline and Duloxetine in reducing cough frequency in patients with refractory…
Refractory Chronic Cough
Mayo ClinicNCT05110144
Phase 1
Group Telehealth Behavioral Cough Suppression Therapy Pilot Study
The purpose of this study is to investigate the effectiveness of behavioral cough suppression therapy (BCST) in managing refractory chronic cough (RCC) within …
Refractory Chronic Cough
University of MontanaNCT06706765
Phase 2
Mechanisms of Change in Behavioral Cough Suppression Therapy for Refractory Chronic Cough
This study is testing new ways to help people who have chronic cough that has not improved with typical treatments. One approach is called behavioral cough sup…
Chronic Cough (CC)Refractory Chronic CoughUnexplained Chronic Cough
University of MontanaNCT06960759