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Yale Steroid Enhanced Versus Exparel Nerveblock TKA Randomized Controlled Trial (RCT) Study
The objective of this phase 2 study is to investigate the efficacy of Dexamethasone sodium phosphate (DEX) plus Methylprednisolone acetate (MPA) in combination…
Swelling Management After Total Knee Arthroplasty: A Randomized Controlled Trial
To determine if inelastic adjustable compression garment results in improved surgical limb swelling control (bioimpedance assessment - primary outcome) after T…
Binaural Beats vs Music of Choice for Early Postoperative Pain After Ambulatory Total Knee and Total Hip Arthroplasty: A Randomized Controlled Trial
To deliver a 30-minute binaural beats audio intervention in PACU and collect pain and anxiety outcomes immediately following surgery, and 4 hours following sur…
Optimizing a Remote-based Physical Activity Intervention for Adults With Total Knee Replacement
The purpose of this study is to identify which supplemental intervention components added to an online exercise program contribute to the greatest increases in…
Sleep Banking Pre-Surgery for Improved Chronic Post-Surgical Pain: A Pilot Study
This study will evaluate the impact of sleep banking on joint replacement surgery recovery.
Spartan Stem, World Cup and World Liner Post Market Clinical Follow-up Study
The aim of the study is to monitor the performance of the Signature Orthopaedics Spartan Stem, World Acetabular Cup and World Liner as a post-market vigilance …
Transcatheter Aortic Prosthesis Function: A Long-term Follow-up Study
In this observational study, the investigators will enroll subjects who underwent TAVR or SAVR more than 3 years ago. Clinical and procedural data from the imp…
Prospective Analysis of Arteriovenous Access Use in Continuous Renal Replacement Therapy, a Feasibility Project
Arteriovenous fistula or graft are the ideal hemodialysis access. Nonetheless the most common access type used for Continuous Renal Replacement Therapy (CRRT) …
Cannabidiol for Postoperative Opioid Reduction in Primary Total Knee Arthroplasty - a Randomized, Two by Two Factorial, Double-blind, Placebo-controlled Clinical Trial
The goal of this study is to better understand how daily treatment with cannabidiol (CBD) affects the need for opioid pain medication, as well as pain, inflamm…
Suzetrigine for Treatment and Reduction of Intense Discomfort After knEe Replacement PAIN
This is a prospective, randomized study. The purpose of this study is to evaluate if the addition of Suzetrigine, a new pain medication, to well established pe…
Evaluating the Impact of Remote Therapeutic Monitoring on Knee Arthroplasty Recovery
The main goal of this study is to see if there is a connection between the social and economic resources available in a patient's neighborhood (measured by the…
A Randomized Controlled Trial of Early Versus Delayed Rehabilitation After Reverse Total Shoulder Arthroplasty for Proximal Humerus Fracture
Proximal humerus fractures can be a debilitating injury in the elderly, impacting the ability to function independently or complete activities of daily living …