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Observational
Randomized Controlled Trial of Video-Laryngoscopy Intervention or Direct Laryngoscopy for Delivery of Less Invasive Surfactant Administration for Premature Infants
Many preterm babies born between 22-28+6 weeks' estimated gestational age (EGA) need surfactant, a medicine that helps the lungs. The goal of the study is to c…
Respiratory Distress Syndrome (Neonatal)Surfactant Deficiency Syndrome Neonatal
University of Texas Southwestern Medical CenterNCT07426016
Phase 3
InfasurfAero™ Versus Sham Treatment in Preterm Newborns With RDS: A Single-dose, Double-blind, Random Allocation, Sham-control, Clinical Trial
The purpose of this clinical study is to determine the effectiveness and safety of Infasurf® administered through the InfasurfAero™, a novel oral airway delive…
Respiratory Distress Syndrome (Neonatal)Intubation ComplicationDeath; Neonatal
ONYNCT05960929
Phase 2
A Phase 2 Crossover Trial of Pressure Targeted High Flow Therapy in Premature Infants
The goal of this study is to see if a new approach to breathing support ('Pressure Targeted High Flow') is as effective as standard of care ('Continuous Positi…
Preterm InfantsRespiratory Distress Syndrome (Neonatal)BPD - Bronchopulmonary Dysplasia
University of Texas at AustinNCT07418502
Observational
Surfactant Prophylaxis in LAte Preterm to Early Term Infants Using a Supraglottic Airway Device to Help Improve Outcomes
The purpose of this research is to learn new information that may help other infants that have respiratory distress syndrome and need breathing support after b…
Respiratory Distress Syndrome (Neonatal)Surfactant
Sharp HealthCareNCT07176117