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1,375 recruiting studies matching your filters

Restarting Triple Therapy With Robust Monitoring for Adverse Events (RETRIAL)

RETRIAL is a multi-site observational study of people with Cystic Fibrosis (PWCF) ages 6 and up starting the new triple-therapy modulator (vanzacaftor/tezacaft…

Cystic Fibrosis

Estimated

~$10 – $750

Boston Children's HospitalNCT06683092

Phase 4

Effect of Hypertonic Saline on Mucociliary Clearance in Non-CF Bronchiectasis

The purpose of this single arm clinical trial is to evaluate the effects of 7% hypertonic saline (HS) delivered by nebulizer on clearance of mucus from the lun…

BronchiectasisNon-cystic Fibrosis Bronchiectasis

Estimated

~$10 – $6,250

University of North Carolina, Chapel HillNCT06242795

Antibiotic Concentrations After MassivE Transfusion (ACME) Study

Combat and civilian trauma frequently result in open wounds that are at risk for infection. Data from the Department of Defense Trauma Registry demonstrate tha…

Adverse Effects in the Therapeutic Use of Other and Unspecified Agents Affecting Blood Constituents

Estimated

~$10 – $750

Brooke Army Medical CenterNCT06699901

AI Medical Interviewing and Diagnostic System Performance Evaluation: One-Shot Vision Differential Diagnosis (OSVDE) and Multi-Step Conversational Non-Inferiority (MSCNE) Evaluation.

This study evaluates the diagnostic performance of a multimodal artificial intelligence (AI) system (AIMD.1) using de-identified medical images and semi-synthe…

Differential DiagnosisDiagnostic Accuracy

Estimated

~$10 – $1,050

Magic Health Inc. (d.b.a. Nolla Health)NCT07470463

Phase 2

A Randomized Controlled Study of Targeted Medical Therapy Versus Placebo for Angina and Non- Obstructive Coronary Arteries: The MVP-ANOCA Study

The goal of this clinical trial is to learn if targeted medical therapy will improve symptoms and quality of life in patients with angina and non-obstructive c…

Angina PectorisMicrovascular AnginaVasospastic Angina+1 more

Estimated

~$10 – $6,250

Stanford UniversityNCT06424834

A Prospective Observational Study of Foam Sclerotherapy for the Treatment of Symptomatic Kidney or Liver Cysts in Patients With Autosomal Dominant Polycystic Kidney and Liver Disease.

An observational prospective study to determine the impact of foam sclerotherapy of large, dominant kidney/liver cysts on quality of life outcomes and kidney/l…

Autosomal Dominant Polycystic KidneyRenal CystAutosomal Dominant Polycystic Liver Disease+1 more

Estimated

~$10 – $750

Mayo ClinicNCT04111692

Phase 1

Optimization of Deep Brain Stimulation Parameters in Patients With Medically Refractory Epilepsy

Deep brain stimulation (DBS) is used to treat epilepsy in cases where patients are medically refractory and are not candidates for surgical resection. This the…

Refractory EpilepsyDeep Brain Stimulation

Estimated

~$10 – $6,250

University of MinnesotaNCT05493722

Phase 1

CROSSCHECK-001: A Phase 1, Open-Label, Dose-Escalation Study to Evaluate Safety, Tolerability, and Clinical Activity of CBX-250 in Participants With Relapsed or Refractory Myeloid Leukemias

Study CBX-250-001 is a Phase 1, open-label, dose-escalation study of CBX-250 in participants with relapsed/refractory AML, HR-MDS, CMML, and CML. Participants …

High-risk Myelodysplastic SyndromeChronic Myelomonocytic Leukemia (CMML)AML - Acute Myeloid Leukemia+1 more

Estimated

~$10 – $8,750

Crossbow Therapeutics, Inc.NCT06994676

Observational

Comparison of the Efficacy of Using a Traction Device in Colonic Endoscopic Submucosal Dissection Versus Conventional ESD: A Randomized Clinical Trial

The goal of this prospective, randomized, controlled trial conducted at Baylor St. Luke's Medical Center is to compare the effectiveness and clinical outcomes …

Gastrointestinal Neoplasm

Estimated

~$10 – $6,250

Baylor College of MedicineNCT06159634

Phase 1

A Phase I Study to Investigate the Safety, Tolerability, and Preliminary Efficacy of Anti-CD30 Bispecific Antibody-Armed Anti-CD3-Activated Autologous T-Cells (CD30 biAb-AATC) in Patients With Relapsed/Refractory CD30 Positive Hematopoietic Malignancies

This first-in-human trial will assess the safety, feasibility, and efficacy of an immunotherapy with a novel CD30 antibody conjugated to a CD3 antibody that is…

Hodgkin DiseaseCD30-Positive Diffuse Large B-Cell LymphomaCD30+ Anaplastic Large Cell Lymphoma+4 more

Estimated

~$10 – $6,250

Medical College of WisconsinNCT05544968

The PCOS Challenge Study: For the Collection of Information to Advance Research and Improve Care for PCOS Patients

The primary purpose of The PCOS Challenge Study will be to conduct high-quality research where patients are included in the design, and answering the questions…

Polycystic Ovary Syndrome

Estimated

~$10 – $1,125

PCOS Challenge: The National Polycystic Ovary Syndrome AssociationNCT05797909

Phase 2

A Phase 2, Open-label, Multiple Ascending-Dose Study to Evaluate the Safety, Tolerability and Efficacy of ARCT-032 in People With Cystic Fibrosis

ARCT-032-02 is a Phase 2, open-label, multicenter, multiple-ascending dose study of ARCT-032 in adults with CF who are not eligible for CFTR modulator therapy …

Cystic FibrosisCFTR Gene Mutation

Estimated

~$10 – $8,750

Arcturus Therapeutics, Inc.NCT06747858