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1,369 recruiting studies matching your filters

Phase II Trial of Alpelisib With iNOS Inhibitor and Nab-paclitaxel in Patients With HER2 Negative Metastatic or Locally Advanced Metaplastic Breast Cancer (MpBC)

This is a research study to test the safety and effectiveness of using the drug alpelisib together with chemotherapy (nab-paclitaxel) and a drug called L-NMMA …

HER2-negative Breast CancerMetastatic Breast CancerMetaplastic Breast Carcinoma+1 more

Estimated

~$10 – $6,250

The Methodist Hospital Research InstituteNCT05660083

Phase 2

Phase 2 Study of Avapritinib in Patients With CKIT or PDGFRA Mutation-Positive Malignant Solid Tumors

This phase II trial studies the effect of avapritinib in treating malignant solid tumors that have a genetic change (mutation) in CKIT or PDGFRA and have sprea…

Anatomic Stage IV Breast Cancer AJCC v8Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8+26 more

Phase 1

A Pilot Study of Chemoprevention With Tamoxifen in Patients With Pre-Invasive Pancreas Mucinous Cystic Neoplasms Who Will Not Undergo Immediate Resection

Pancreatic mucinous cystic neoplasm (MCN) is a precursor to invasive pancreatic adenocarcinoma which occurs almost exclusively in females in their 5th-7th deca…

Pancreatic CystPancreatic Mucinous Cystic Neoplasm

Estimated

~$10 – $6,250

University of NebraskaNCT06320990

Cardiovascular Outcomes and Relative Energy Deficiency in Division I HBCU Athletes: CORE-DI Study

Low energy availability (LEA) occurs when the body does not get enough calories to support both daily life and exercise. This can happen when athletes train ha…

Vascular StiffnessHypertension (HTN)Nutritional Deficiency Related Cardiovascular Risk in Athletes

Estimated

~$10 – $750

North Carolina Agriculture & Technical State UniversityNCT07583940

Phase 1

Sequential Decitabine in Combination With FLAG-Ida Followed Immediately by Reduced-Intensity Conditioning (RIC) Allogeneic Hematopoietic Cell Transplantation (DEC-FLAG-Ida/RIC) for Adults With Myeloid Malignancies at High Risk of Relapse: A Phase 1/2 Study

This phase I/II trial studies the safety, side effects, and best dose of decitabine in combination with fludarabine, cytarabine, filgrastim, and idarubicin (FL…

Acute Myeloid LeukemiaAcute Undifferentiated LeukemiaMixed Phenotype Acute Leukemia+11 more

Estimated

~$10 – $6,250

Phase 1

A Phase 1/2, Multicenter, Open-Label, First-in-Human Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of DB-1324 in Participants With Advanced/Metastatic Gastrointestinal Tumors

This study, the first clinical trial, aims to determine the safety, tolerability, pharmacokinetics, pharmacodynamics, maximum tolerated dose, and antitumor act…

Gastrointestinal Cancer

Estimated

~$10 – $8,750

DualityBio Inc.NCT07263594

Observational

Clareon TruPlus Single-Arm Study

The purpose of this research study is to generate safety and performance data for Clareon TruPlus Monofocal Intraocular Lenses (IOLs). IOLs are medical devices…

AphakiaAstigmatism

Estimated

~$10 – $7,500

Alcon ResearchNCT07502456

Phase 4

Doxycycline Prophylaxis for Prevention of Sexually Transmitted Infections Among Adolescent and Young Adult Females in the United States

The goal of this open-label, randomized trial is to assess the efficacy of doxycycline prophylaxis in reducing incidences of bacterial sexually transmitted inf…

GonorrheaChlamydiaSyphilis+1 more

Estimated

~$10 – $7,500

WestatNCT06738407

A Prospective, Longitudinal and Observational Natural History Study for Children and Adults With Baker Gordon Syndrome - Genetic Autism Alliance

The goal of this study is to conduct a prospective, longitudinal assessment of the natural clinical progression of children and adults with Synaptotagmin1-Asso…

Rare DiseasesAutism or Autistic TraitsDevelopment Delay+4 more

Estimated

~$10 – $750

University of Missouri-ColumbiaNCT06399952

Observational

Human Papillomavirus Self-Sampling Options to Promote Equity (HOPE)

This study is testing a new way to help people who are unhoused get screened for cervical cancer. Cervical cancer can often be prevented if it is found early. …

Uterine Cervical NeoplasmsHPV TestingPap Smear

Estimated

~$10 – $6,250

University of ArizonaNCT07214506

Genetic Study of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)

Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) is a condition with several causes of which some remain unknown. It is believed that some types of C…

Chronic Prostatitis (CP)Chronic Pelvic Pain Syndrome (CPPS)Painful Bladder Syndrome (PBS)+2 more

Estimated

~$10 – $750

Boston Children's HospitalNCT00499317

Observational

Reducing Blood Pressure in Mid-life Adult Binge Drinkers: the Role of Microvascular Function and Sympathetic Activity

This study has two phases: Phase 1 is to examine blood pressure, microvascular function, and sympathetic nerve activity in mid-life adult binge drinkers vs. a…

Alcohol DrinkingBinge DrinkingBlood Pressure+5 more

Estimated

~$10 – $6,250

The University of Texas at ArlingtonNCT05522075