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The ARDS, Pneumonia, and Sepsis (APS) Consortium: A Prospective Observational Study to Evaluate Phenotypes
The goal of the observational APS phenotyping study is to better understand risk factors, potential biomarkers, length and severity of illness, and recovery fo…
Virtual Reality in ICU (PARTNER) - A Research Study About Engaging in Strategies to Promote Relaxation, Improve Your Mood, and Stimulate Thinking in the Intensive Care Setting
This project is designed to have patients participate in a virtual environment with various tasks such as breathing exercises, games to help the brain, and tec…
TriVerity™ for Improved Management of Emergency Department (ED) Patients With Suspected Infections
A pre/post interventional use trial, with ED patients who are initially triaged to locations other than a dedicated patient room in the main ED (e.g., waiting …
A Phase III, Open Label, Randomized, Controlled Study of VBI-S in the Treatment of Hypovolemia in Patients With Septic Shock
This study is being conducted to evaluate the safety and effectiveness of VBI-S in elevating the blood pressure of septic shock patients with absolute or relat…
Reducing Empiric VAncomycin Use in Pediatric Suspected Sepsis (REVAMP-Sepsis)
The goal of this quasi-experimental interventional study is to determine the effectiveness of a multifaceted stewardship intervention in reducing overall vanco…
Neutrophil Phenotypic Profiling and Organ Injury Assessment in Patients With Sepsis
In this research study we want to learn more about the character of neutrophils that are present in the blood of children with sepsis. Sepsis is a severe type …
Surgical Critical Care Initiative (SC2i) Tissue and Data Acquisition Protocol (TDAP) in Burn Patients Improving the Robustness and Generalizability of Post-burn Sepsis Prediction With the Post-Burn Sepsis Digital Twin. Group 1
This study is following adult patients with serious burn injuries to better understand how their bodies respond to treatment and recovery. Researchers will col…
Full Title: Sepsis Early Prediction System Score (SEPSys Score) and RESCUE Score Multi-Site, Two-Intervention, Cluster-Randomized, Factorial Stepped-Wedge Pragmatic Clinical Trial at the University of Mayland Medical System
This study is designed to test two new risk scores - one designed to predict a patient's four-hour risk of developing sepsis and one designed to predict a pati…
Prediction of Rehospitalization Following a Sepsis Admission Using a Wearable Biopatch and Deep Learning Model
The goal of this observational study is to learn about the utility of biopatches predicting 30-day readmissions in patients discharged from the hospital with s…
Role of Transposable Elements in Septic Immune Aging
The goal of this observational study is to learn about how transposable element levels affect the patient outcomes in sepsis. The main questions it aims to ans…
Evaluation of Mitral Annulus Systolic Plane Excursion (MAPSE) in Emergency Department Patients With Sepsis
Patients with bloodstream infections (sepsis) have been found in prior studies to have infection-related heart dysfunction, even if they did not have preexisti…
Assessing Immune Dysfunction in Sepsis
Sepsis leads to sustained immune system dysfunction resulting in increased susceptibility to secondary infection while in the hospital or after discharge. Cons…