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10 recruiting studies matching your filters

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma

The objective of this study is to assess the potential for GB-0895 treatment to improve the health of adolescents and adults with severe asthma that is uncontr…

Severe Asthma

Estimated

~$10 – $7,500

Generate BiomedicinesNCT07359846

Phase 3

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma

The objective of this study is to assess the potential for GB-0895 treatment to improve the health of adolescents and adults with severe asthma that is uncontr…

Severe Asthma

Estimated

~$10 – $7,500

Generate BiomedicinesNCT07276724

Observational

Randomized, Controlled, Multi-Center, Delayed Activation Feasibility Clinical Study to Evaluate the Safety and Efficacy of Pulmonary NeuroModulation (PNM) for the Treatment of Subjects With Moderate to Severe Uncontrolled Asthma - PULSAR: Pulmonary Stimulation for Asthma Relief

This study aims to assess the safety and efficacy of Pulmonary Neuromodulation in patients suffering from moderate to severe asthma

Moderate to Severe Asthma

Estimated

~$10 – $8,750

Spiro Medical, Inc.NCT07709754

Phase 4

CHEST: A Collaboration With Community HEalth Centers to Implement SmarT for Asthma

Purpose: This study aims to improve asthma care by helping clinicians at community health centers prescribe a guideline-recommended treatment called SMART (Sin…

Moderate to Severe Asthma

Estimated

~$10 – $6,250

Washington University School of MedicineNCT07241117

Phase 2

A Phase 2 Randomized Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Three Doses of Frevecitinib (KN-002) in Patients With Severe Asthma

A Phase 2 Dose Ranging Study to Evaluate the Efficacy and Safety of Frevecitinib (KN-002) Over a 12-Week Treatment Period in Patients With Severe Asthma Not Co…

Severe Asthma

Estimated

~$10 – $8,750

Kinaset Therapeutics IncNCT07532265

Phase 4

Fasenra Demonstrates Durability Over the Full 8-week Treatment Period

The goal of this observational study is to learn more about the effectiveness of benralizumab (Fasenra, 30 mg every 8 weeks) in maintaining asthma control in p…

Eosinophilic AsthmaSevere AsthmaSevere Eosinophilic Asthma+1 more

Estimated

~$10 – $7,500

Endeavor HealthNCT07654842

Evaluation of Ventilation Defects Downstream of Mucus Plugs in Patients With Muco-Obstructive Lung Disease

In this study, xenon MRI will be used to evaluate regional functional consequences of mucus plugs in the lungs of patients with muco-obstructive pulmonary dise…

Severe AsthmaCOPDNon-CF Bronchiectasis+1 more

Estimated

~$10 – $750

University of Kansas Medical CenterNCT06985225

Phenotyping Asthma for Bronchial Thermoplasty: Airway Smooth Muscle Structure and Function

This study will evaluate a new imaging technology, called optical coherence tomography (OCT) to examine the asthmatic airways before and after bronchial thermo…

Severe Asthma

Estimated

~$10 – $750

Massachusetts General HospitalNCT03435237

Downstream Effects of Airway Mucus Plugs on 129Xenon MRI Following Biologic Therapy

In this study, xenon MRI will be used to evaluate regional functional consequences of mucus plugs in the lungs of patients with severe asthma. Mucus plugs will…

Severe Asthma

Estimated

~$10 – $1,125

Bastiaan DriehuysNCT07139899

Phase 4

Leveraging Pharmacogenomics in Asthma for Predication, Mechanism and Endotyping

In this study, a new method will be used to evaluate response to 2 approved biologic therapies, and assess how well each patient responds to each asthma treatm…

Moderate to Severe Asthma

Estimated

~$10 – $6,250

University of California, San DiegoNCT06385236