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5 recruiting studies matching your filters

Operant Conditioning of Spinal Reflexes to Enhance Motor Function Recovery After Spinal Cord Injury

The purpose of this study is to validate the capacity of a reflex training system to change the size of the targeted reflex. For this, the researchers are recr…

Spinal Cord InjuriesNeurological InjuryParalysis+1 more

Estimated

~$10 – $6,250

Medical University of South CarolinaNCT05094362

Phase 1

A Phase 1/2 Open-label Intrathecal Administration of MELPIDA to Determine Its Safety and Efficacy for Patients With Spastic Paraplegia Type 50 (SPG50) Caused by Mutation in the AP4M1 Gene.

MELPIDA is proposed for the treatment of subjects with SPG50 and targets neuronal cells to deliver a fully functional human AP4M1 cDNA copy via intrathecal inj…

Spasticity, MuscleMicrocephalyIntellectual Deficiency+3 more

Estimated

~$10 – $8,750

Elpida Therapeutics SPCNCT05518188

Observational

Control of Incomplete Spinal Cord Injury-Related Spasticity by Means of Vibrotactile Coordinated Reset Fingertip Stimulation

The purpose of our study is to evaluate vibrotactile Coordinated Reset (vCR) and its effects on spasticity symptoms in incomplete spinal cord injured patients.…

Spasticity, MuscleSpinal Cord Injuries

Estimated

~$10 – $6,250

Stanford UniversityNCT06290609

Investigating the Genetic Basis of Hereditary Spastic Paraplegia

The purpose of the HSP Sequencing Initiative is to better understand the role of genetics in hereditary spastic paraplegia (HSP) and related disorders. The HSP…

Hereditary Spastic ParaplegiaNeurodegenerative DiseasesPediatric Disorder+3 more

Estimated

~$10 – $750

Boston Children's HospitalNCT05354622

Observational

A Randomized, Sham Controlled Trial of Dorsal Root Rhizotomy Stereotactic Radiosurgery Versus Standard of Care for Spasticity Associated With Stroke, Spinal Cord Injury & Cerebral Palsy

A scientific study is being done to test a special treatment for people who have spasticity or tight muscles. This treatment is called "stereotactic radiosurge…

Spasticity as Sequela of StrokeSpastic Cerebral PalsySpasticity, Muscle

Estimated

~$10 – $6,250

Ohio State UniversityNCT06070233