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Massachusetts General HospitalNCT07725289

Mental HealthSubstance Use DisordersCo-occurring Mental and Substance Use Disorders

Supporting Treatment Access and Recovery in Re-entry (STAR-R)

This application is aimed at testing a multicomponent intervention called "Maintaining Independence and Sobriety through Systems Integration, Outreach, and Net…

University of Massachusetts, WorcesterNCT07555145

Substance Use DisordersPosttraumatic Stress SymptomAnxiety

The Effect of the Safe and Sound Protocol on Emotional Regulation in Traumatized Adults With Substance Use Disorders

This study will explore whether the use of the Safe and Sound Protocol (SSP) app is an effective adjunct to treatment as usual (TAU) in individuals with co-occ…

Caron Treatment CentersNCT07219056

~$10 – $7,500

Substance UseHIV Infections

Couples Motivational Interviewing to Reduce Drug Use and HIV Risk in Vulnerable Male Couples

This study utilizes a randomized controlled trial design to evaluate the efficacy of couples motivational interviewing (MI) to reduce the frequency and severit…

Hunter College of City University of New YorkNCT06307977

Asperger's DisorderAsperger DisorderAutism Disorder+41 more

QAIAx (AIhealth4U) - AI Smart Health Cities: Microcity Enclave Program (UPSTO App No(s). 64/074,526, 64/063,557, 64/105,164, 63/903,181, 63/729,428) is Frontier AI/AGI Public Health Trials Sandbox Framework That Provides Free Public Health Services to Registered and Sponsored Visitors/Occupants for RDT&E Under 28 U.S.C. 1498 (Classified as a PPA, OTA Under 10 U.S. Code 4001, 4022), Serving as a Global Intranet of Humans Resident Patients Among Multiple Enclave Communicates ("AI Microcities" or "Smart Health Cities") Living and Learning With AI Robotics for Non-medicinal Treatment.

BRIEF SUMMARY A. "What is the purpose of this study?" BACKGROUND. The QAIAx clinical trial (Quantum AI/AGI Public Health Agency), known operationally as the …

Support PersonsFamily MembersChosen Family+4 more

Recovery Inspired Support Engagement (RISE) Pilot

The goal of this clinical trial is to learn if a 1-on-1 support program is easy to complete and acceptable for people supporting loved ones who have recently r…

Mclean HospitalNCT07519759

Substance Use Disorder (SUD)

Neurofeedback to Reduce Anhedonia and Improve Outcomes in Opioid Use Disorder: a Feasibility Study

This feasibility study collects initial data on the use of an fMRI neurofeedback protocol for treating anhedonia in methadone-treated individuals with opioid u…

Yale UniversityNCT07768007

HIVSubstance Use Disorder (SUD)

Project SHIELD 2.0: Police Education to Support Public Health in Kentucky

The project is a pragmatic, quasi-experimental hybrid type II effectiveness-implementation trial of a structural HIV prevention intervention to address police …

Johns Hopkins Bloomberg School of Public HealthNCT07804121

~$10 – $5,625

Substance Use Disorder (SUD)

Auricular Vagal Neuromodulation Therapy (AVNT™) for the Alleviation of Depression and Anxiety in Substance Use Disorder

This pilot study will evaluate whether home-based auricular vagal neuromodulation therapy (AVNT) is practical, acceptable, and well tolerated for adults receiv…

Daisy Thompson-LakeNCT07814755

~$10 – $7,500

DepressionAnxietyPost Traumatic Stress Disorder+6 more

Efficacy of a Multi-level School Intervention for LGBTQ Youth

Washington University School of MedicineNCT05541406

Nicotine Use DisorderSubstance Use Disorders

Temporal Interference Methods for Addiction Treatment

This clinical study is testing whether a new non-invasive brain stimulation method, called temporal interference (TI), can reduce nicotine cravings and usage i…

Indiana UniversityNCT07210268

Major Depressive DisorderSubstance Use DisorderNormal Physiology

Defining Neurobiological Links Between Substance Use and Mental Illness

Background: Nicotine dependence leads to about 480,000 deaths every year in the United States. People with major depressive disorder (MDD) are twice as likely…