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6 recruiting studies matching your filters

Pilot Studies Blocking Injury-Induced MVP Release in Skin Using Topical Amitriptyline

The purpose of this study is to determine the amount of substances contained in skin known as microvesicle particles (MVP). Studies suggest these MVP are invol…

Thermal BurnAmitriptyline

Estimated

~$10 – $6,250

Wright State UniversityNCT07716722

Phase 3

Plasma Resuscitation Early for Evaluating Volume and Endotheliopathy of Thermal Injury (PREEVEnT) Trial

The Plasma Resuscitation Early for Evaluating Volume and Endotheliopathy of Thermal Injury (PREEVEnT) trial will be a 5-year (3-year enrollment), open label, p…

Burn InjuryThermal Burn

Estimated

~$10 – $7,500

Jason SperryNCT07212998

Phase 1

Pilot Studies Testing the Use of Oral Amitriptyline in Reducing Localized Burn Injury-induced Microvesicle Particle Release

The purpose of this study is to determine the amount of substances contained in skin known as microvesicle particles (MVP). The hypothesis to be tested in this…

Microvesicle ParticlesThermal Burn

Estimated

~$10 – $6,250

Wright State UniversityNCT07640061

Phase 3

A Phase III Open-Label, Multicenter, Randomized, Controlled Clinical Trial to Evaluate the Safety and Efficacy of realSKIN® to Provide Complete Wound Closure of Mixed-Depth, Full-Thickness Burn Wounds as an Alternative to Autografting

To evaluate the safety and efficacy of realSKIN® to provide complete wound closure of mixed-depth, full-thickness burn wounds as an alternative treatment to au…

Burns Degree ThirdBurn (Disorder)Burn Degree Second+2 more

Estimated

~$10 – $8,750

XenoTherapeutics, Inc.NCT06223269

Phase 2

A Phase 2a, Open-Label Study of the Safety, Tolerability, and Pharmacokinetics of a Single Dose of cP12 in Otherwise Healthy Adults With Up To and Including 10% Total Body Surface Area Thermal Burns

This is a Phase 2a, open-label, single-dose study to evaluate the safety, tolerability, and PK profile of cP12 in 6 male and female subjects with thermal burns…

Thermal Burns

Estimated

~$10 – $8,750

Neomatrix Therapeutics, Inc.NCT06814717

Observational

Virtual Reality-Enhanced Progressive Muscle Relaxation for Symptom Management in Burn Survivors

The goal of this clinical trial is to learn whether progressive muscle relaxation (PMR), delivered either alone or enhanced with virtual reality (VR), can help…

BurnChronic Pain Following Thermal Burn InjuryNon-Pharmacological Interventions+8 more

Estimated

~$10 – $6,250

Johns Hopkins UniversityNCT07317271