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136 recruiting studies matching your filters

Phase 1b/2a Clinical Study of AL58805 Combining With Other Anti-tumor Agents in Advanced, Metastatic GYN, STS or Breast Cancers

This phase 1b/2a study evaluates AL58805, an oral investigational drug that blocks PI3K and mTOR signaling, in combination with one of three anticancer treatme…

Endometrial NeoplasmsSoft Tissue Sarcoma (STS)Breast Neoplasms

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Advenchen Pharmaceuticals, LLC.NCT07811232

Phase 4

Superiority of Phenylephrine Versus Norepinephrine in Complex Spine Surgery (SPiNeS): A Prospective Randomized Superiority Trial

The purpose of this research is to compare two commonly used medications, phenylephrine and norepinephrine, that are used to treat low blood pressure during co…

Spine SurgeryIntraoperative HypotensionTissue Perfusion

Estimated

~$25 – $1,000

Actual pay is set by the research site.

Mayo ClinicNCT07796282

Phase 2

Bacterial Decolonization Plus Intraoperative Indocyanine Green Angiography for Soft Tissue Sarcomas of the Lower Extremity Receiving Preoperative Radiotherapy (CONCERTO)

This trial will investigate the combination of two low-cost, non-toxic strategies to assess whether they can reduce the risk of acute major wound complications…

Sarcoma,Soft Tissue

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Adam OlsonNCT06712433

Observational

Bridging Adolescent and Young Adult Sarcoma Survivors With Personalized Oncology Exercise Service (AYA-ONE): A Pilot Intervention

This study will evaluate strategies to improve physical function and promote exercise and physical activity in adolescents and young adults (AYAs) with sarcoma…

SarcomaBone SarcomaSoft Tissue Sarcoma (STS)

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Dana-Farber Cancer InstituteNCT07662239

Phase 1

Positron Emission Tomography (PET) Imaging of the Enhanced Permeability and Retention (EPR) Effect With [89Zr]DFO-starPEG in Patients With Solid Tumors

This is a first-in-human, pilot study of the novel PET-imaging radiotracer \[89Zr\]DFO-starPEG. The study is designed to obtain preliminary data to support fut…

Solid TumorSolid CarcinomaSoft Tissue Lesion

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Robert Flavell, MD, PhDNCT06894745

Phase 4

Restoring Facial Volume After GLP-1 Weight Loss With Radiesse

The goal of this clinical trial is to evaluate the potential of Calcium Hydroxylapatite (CaHA) to restore facial volume and improve skin quality in patients wi…

Volume Loss (Soft Tissue Ptosis or Atrophy )

Estimated

~$25 – $1,500

Actual pay is set by the research site.

Kalpna Kay Durairaj, MD, FACSNCT07419854

Phase 2

A Phase 2, Multicenter, Open-label Study of Lifileucel (Tumor-infiltrating Lymphocytes [TIL]) in Participants With Previously Treated Advanced Soft Tissue Sarcoma

A study of lifileucel (tumor-infiltrating lymphocytes) in adults with advanced soft tissue sarcoma ('SARATOGA')

SarcomaSoft Tissue Sarcoma (STS)Advanced Soft Tissue Sarcoma+2 more

Estimated

~$75 – $2,800

Actual pay is set by the research site.

Iovance Biotherapeutics, Inc.NCT07741877

Phase 2

Preoperative 5-Day Radiotherapy for Soft Tissue Sarcoma: A Single Institution Phase II Trial

The purpose of this research study is to preserve healthy tissue around the cancer on the arm(s) and/or leg(s) using Hypofractionated radiotherapy, while treat…

Soft Tissue Sarcoma

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Medical University of South CarolinaNCT06905132

Phase 1

Evaluation of In-Vitro Cryo Therapeutic Intervention on Human Cellular Samples - Truway Health Cryogenics Pilot Study

This laboratory-based study evaluates the effects of controlled cryogenic preservation on human cell samples using Truway Health's in-vitro cryo therapeutic me…

Cellular Injury and Post-Cryogenic RecoveryCryogenic Cellular StressCold-Induced Cellular Injury+8 more

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Truway Health, Inc.

Observational

PROspective Phase II Trial of Pre-operative Hypofractionated protoN Therapy for Extremity and Truncal Soft Tissue sarcOma

This study is being done to examine whether proton therapy for certain kinds of sarcomas (extremity and trunk soft tissue) is safe and effective. As part of th…

Soft Tissue Sarcoma

Estimated

~$10 – $750

Actual pay is set by the research site.

Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsNCT05917301

Phase 1

SAINT: A Phase 1/2 Study of Safe Amounts of IPLIMUMAB, NIVOLUMAB and TRABECTEDIN for Previously Treated Advanced Soft Tissue Sarcoma (STS)

This is an open label, dose-seeking phase 1/2 study using escalating doses of TRABECTEDIN given intravenously with defined doses of IPILIMUMAB and NIVOLUMAB ba…

Advanced Soft Tissue SarcomaMetastatic Soft Tissue Sarcoma

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Sarcoma Oncology Research Center, LLCNCT03138161

Heart Institute Biobank & Registry for Adult Congenital Heart Disease and Related Disorders

A repository of biospecimens and detailed phenotypic information collected longitudinally from adults with congenital heart disease and related conditions, wit…

Adult Congenital Heart DiseasePulmonary HypertensionConnective Tissue Disease+1 more

Estimated

~$10 – $675

Actual pay is set by the research site.

Children's Hospital Medical Center, CincinnatiNCT07477197