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Effect of Testosterone on Brain Imaging and Headache in Transmasculine Adolescents
Transmasculine youth (female sex assigned at birth, male gender identity) who begin clinical gender affirming hormone therapy (GAHT) with testosterone (T) may …
TransHealthGUIDE: Transforming Health for Gender-Diverse Young Adults Using Interventions to Drive Equity
This is a randomized controlled trial to test the effectiveness of an interactive educational app-based digital intervention that provides knowledge and suppor…
Effects of Puberty and Pubertal Suppression on Insulin Sensitivity, Metabolic Rate and Vascular Health
This observational study will evaluate the effect of puberty suppression on insulin sensitivity, metabolic rate and vascular health among transgender female yo…
Economic Navigation and Strengthening to Research Unrestricted Services for Transgender Women (ENTRUST)
The overall hypothesis is that stabilizing transgender women financially while providing them tailored counselling will increase their odds of them linking to …
Research Participation With Transgender and Gender-Diverse Youth
Research has historically excluded the participation of transgender and gender-diverse people. The purpose of this research study is to find out about what goe…
Developing an Online Intervention Addressing Transgender/Nonbinary Young Adults' Experiences With Alcohol and Romantic Relationships
The objective of this study is to learn more about Whole Selves, an interactive online resource ("intervention") to help transgender and/or nonbinary young adu…
Cervical and Endometrial Cancer Screening in Patients Seeking Gender-Affirming Hysterectomy
This study aims to quantify the rates of cervical cancer screening and endometrial sampling prior to gender-affirming hysterectomy, assess the need for these t…
Androgen Effects on the Reproductive Neuroendocrine Axis, 2025 Version
This research study investigates whether male-level exogenous androgens inhibit the reproductive neuroendocrine axis in otherwise healthy (non-PCOS) females.
Novel Delivery Method of Transgender Voice Therapy Using a Mobile Application
The investigators hypothesize that the mobile application they developed for transgender and gender diverse individuals (TGGD) will be equivalent or better tha…
Pubertal Blockade and Estradiol Effects on Cardiometabolic Health for Transitioning Youth
To evaluate the effect of estradiol with or without a prior gonadotropin releasing hormone analogue on insulin sensitivity and vascular function in transgender…
Effects of Oral Progesterone in Transgender Women on Breast Development, Sleep Quality, Psychological Distress, and Cardiovascular Risk
This study aims to study the effects of Oral Progesterone in Transgender Women. The primary goal is to study the effect of progesterone on psychological distre…