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7 recruiting studies matching your filters

Self-Supporting Nasopharyngeal Airway (ssNPA) Treating Upper Airway Obstruction in Hypotonia

The researchers are investigating if the Self-Supporting Nasopharyngeal Airway (ssNPA) device can be used in the treatment of obstructive sleep apnea in childr…

Obstructive Sleep ApneaHypertonia, MuscleNasal Airway Obstruction+3 more

Estimated

~$10 – $6,250

University of MichiganNCT05527652

Phase 2

Cholinergic Integrity in Down Syndrome in Association With Aging, Alzheimer's Disease Pathology, and Cognition

Progressive age-related cognitive deficits occurring in both AD and DS have been connected to the degeneration of several neuronal populations, but mechanisms …

Down SyndromeDown Syndrome, Partial Trisomy 21Alzheimer Disease

Estimated

~$10 – $6,250

Vanderbilt University Medical CenterNCT05231798

ADVANCE Study: Assay Development and Validation for Pre-Natal and Obstetric Conditions

The goal of the ADVANCE (Assay Development and Validation for Pre-Natal and Obstetric Conditions) study is to compare the concordance of results of a novel non…

Pregnant IndividualsAneuploidyDown Syndrome (Trisomy 21)+4 more

Estimated

~$10 – $1,050

BillionToOne Inc.NCT07643896

Vascular Function in Adults With Down Syndrome

Adults with Down syndrome (Ds) are often thought to have a lower risk of heart and blood vessel disease because they tend to have lower blood pressure and fewe…

Down Syndrome (Trisomy 21)

Estimated

~$10 – $750

University of Nevada, Las VegasNCT07630207

Research to Develop the Human Trisome Project Biobank

The Human Trisome Project will significantly increase the speed of Down syndrome research and the understanding of associated medical conditions. Its biobank w…

Down SyndromeTrisomy 21

Estimated

~$10 – $750

University of Colorado, DenverNCT02864108

Observational

Improving Sleep and Quality of Life in Individuals With Down Syndrome and Their Caregivers

Aim 1 of the proposed project will be to adapt the virtual Mindfulness-Based Therapy for Insomnia (MBTI) for individuals with Down syndrome (DS). The investiga…

Down SyndromeDown Syndrome (Trisomy 21)

Estimated

~$10 – $6,250

University of Alabama at BirminghamNCT06783725

Functional and Neurodevelopmental Outcomes Following Intensive Multimodal Neurorehabilitation in Pediatric Patients With Neurodevelopmental Disorders, Including Chromosomal Abnormalities

This observational study evaluates functional and developmental outcomes in pediatric participants undergoing a two week intensive multimodal neurorehabilitati…

Neurodevelopmental DisordersNeurodevelopmental Disorders (NDD)Neurodevelopmental Disorders and Developmental Abnormalities+20 more

Estimated

~$10 – $1,125