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27,292 recruiting studies available now

Barostim-Enabled NEurohormonal Intervention For Improving Treatment of Heart Failure (BENEFIT-HF)

The purpose of BENEFIT-HF is to demonstrate the safety and effectiveness of Baroreflex Activation Therapy (BAT) with the Barostim System in participants with h…

Heart FailureHeart Failure NYHA Class IIHeart Failure NYHA Class III

Estimated

~$10 – $1,050

Actual pay is set by the research site.

CVRx, Inc.NCT07232030

Phase 1

A Phase I Study to Assess the Safety and Antitumor Activity of Autologous B7-H3 Chimeric Antigen Receptor T Cells in Previously Treated Extensive-Stage Small Cell Lung Cancer With Recurrent or Refractory Disease

Background: Small cell lung cancer (SCLC) is the deadliest form of lung cancer. Extrapulmonary neuroendocrine cancer (EPNEC) is a similar type of cancer that …

Recurrent Small Cell Lung CancerExtensive-Stage Small Cell Lung CancerSmall Cell Lung Cancer+6 more

Estimated

~$150 – $2,700

Actual pay is set by the research site.

National Cancer Institute (NCI)

Phase 2

A Proof-of-Concept Open-Label Clinical Trial to Evaluate the Safety, Tolerability, and Efficacy of CSTI-500 in Participants With Prader-Willi Syndrome

This is a proof-of-concept, open-label, dose-escalation study to evaluate the safety, tolerability, pharmacokinetics, and efficacy of CSTI-500 in participants …

Prader-Willi Syndrome

Estimated

~$75 – $2,800

Actual pay is set by the research site.

ConSynance TherapeuticsNCT07348601

Evaluation of a Point-of-Care, AI-Powered Spectroscopy Device for Triage of Suspicious Vulvar Lesions: A Pilot Study

This purpose of this study is to assess the feasibility of using the DermaSensor™ device on vulvar skin.

Vulvar Intraepithelial Neoplasia, HPV-IndependentVulvar Squamous Cell CarcinomaVulvar Squamous Intraepithelial Lesion, HPV-Associated

Estimated

~$10 – $750

Actual pay is set by the research site.

Mayo ClinicNCT07886203

Phase 1

A Multicenter, Open Label, Non-randomized First-in-human Phase 1 Dose Escalation and Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of BAY 3547926 Alone, and in Combination, in Participants With Advanced Hepatocellular Carcinoma (HCC)

In this study, researchers want to learn about the safety of a new drug, BAY 3547926, and how well the drug works in people with a type of liver cancer called …

Hepatocellular Carcinoma

Estimated

~$150 – $4,500

Actual pay is set by the research site.

BayerNCT06764316

Observational

Biometabolic Outcomes After Weight Loss Surgery: An Individualized Approach

Variable outcomes after weight loss surgery are likely attributable to complex, poorly understood mechanisms. Due to the significant impact that morbid obesity…

Obesity, MorbidMetabolic SyndromeNASH - Nonalcoholic Steatohepatitis

Estimated

~$10 – $750

Actual pay is set by the research site.

University of Missouri-ColumbiaNCT04841057

Phase 2

A Phase 2, Open-label, Fixed-dose Study to Assess the Efficacy of Sodium Phenylbutyrate (ACER-001) in Treating Pediatric and Adult Patients With Medium Chain Acyl-CoA Dehydrogenase (MCAD) Deficiency Resulting From the Prevalent ACADM c.985 A>G (K304E) Mutation

This is a medical research study to test a medication in patients 4 years of age and older with a disease called medium-chain acyl-CoA dehydrogenase deficiency…

Medium-chain Acyl-CoA Dehydrogenase Deficiency

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Jerry Vockley, MD, PhDNCT06773026

Data Collection of Standard Care and Evaluation of NHLBI Patients and Donors

Background: Researchers seek ways to study people s medical problems in order to teach and further general knowledge. The ability to assess and treat people w…

Wide Spectrum of DiseasesHematologic Diseases

Estimated

~$10 – $675

Actual pay is set by the research site.

National Heart, Lung, and Blood Institute (NHLBI)NCT04450927

Phase 1

Therapeutic RSK1 Targeting in Myeloid Malignancies

This study hypothesizes that PMD-026, an oral inhibitor of ribosomal protein S6 kinase A1 (RSK1), is safe and well tolerated in participants with myelofibrosis…

Myeloid Malignancy

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Washington University School of MedicineNCT07379125

Observational

Tear Fluid Collection in Patients Before and After Corneal Incision or Trauma.

Tear fluid will be collected from patients diagnosed with ocular trauma at the University of Pittsburgh Medical Center to evaluate biomarkers.

Ocular Trauma

Estimated

~$10 – $1,050

Actual pay is set by the research site.

InnSight Technology, Inc.NCT07887425

Phase 1

A PHASE 1/2A STUDY EVALUATING THE SAFETY, TOLERABILITY, PHARMACOKINETICS, PHARMACODYNAMICS, AND ANTI-TUMOR ACTIVITY OF PF-07220060 AS A SINGLE AGENT AND AS PART OF COMBINATION THERAPY IN PARTICIPANTS WITH ADVANCED SOLID TUMORS

This is a Phase 1/2A, open label, multicenter, nonrandomized, multiple dose, safety, tolerability, pharmacokinetic and pharmacodynamic study of PF-07220060 adm…

LiposarcomaProstate CancerAdvanced Breast Cancer+2 more

Estimated

~$150 – $4,500

Actual pay is set by the research site.

PfizerNCT04557449

Observational

Reliability of Force Measurement Within the Carbon Fiber Orthosis Proximal Cuff

The primary purpose of this research study is to determine if forces within carbon fiber custom dynamic orthoses (CDOs) can be reliability assessed using Loadp…

HealthyAnkle Foot Orthosis (AFO)Peripheral Neuropathy

Estimated

~$10 – $750

Actual pay is set by the research site.

University of IowaNCT06127264