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A Randomised, Double-blind, Placebo-controlled Trial With an Open-label Extension to Assess the Pharmacokinetics, Safety, and Efficacy of Empagliflozin Tablets in Paediatric Patients With Chronic Kidney Disease (EMPA-KIDNEY® Kids)

This study is open to children aged 2 to 17 with chronic kidney disease (CKD). The purpose of this study is to find out if a medicine called empagliflozin help…

Chronic Kidney Disease

Estimated

~$10 – $7,500

Boehringer IngelheimNCT07107945

Phase 1

VRC 329: A Phase I Open-Label, Clinical Trial to Evaluate the Safety, Tolerability, and Immunogenicity of a Quadrivalent Influenza HA Stem Vaccine VRC-FLUMOS0122-00-VP (STEMos1) With and Without ALFQ Adjuvant in Healthy Adults

Background: Influenza (flu) is a contagious respiratory illness caused by viruses. Flu symptoms can range from mild to severe, and the illness can be fatal. V…

Influenza PreventionPandemic Influenza Prevention

Estimated

~$10 – $5,625

National Institute of Allergy and Infectious Diseases (NIAID)NCT07111078

Phase 3

Multinational, Interventional, 52-week, Open-label, Single-arm Study to Evaluate the Treatment Outcomes of Anifrolumab 120 mg Subcutaneous Once Weekly in Immunosuppressant-naïve and Biologic-naïve Systemic Lupus Erythematosus (SUNFLOWER)

The purpose of the SUNFLOWER study is to describe clinical outcomes, including DORIS remission, achieved following the initiation of anifrolumab 120 mg SC once…

Systemic Lupus Erythematosus

Estimated

~$10 – $7,500

AstraZenecaNCT07430306

Phase 3

EASi-PROTKT™ - A Phase III Double-blind, Randomised, Parallel-group Superiority Trial to Evaluate Efficacy and Safety of the Combined Use of Oral Vicadrostat (BI 690517) and Empagliflozin Compared With Placebo and Empagliflozin in Participants With Type 2 Diabetes, Hypertension and Established Cardiovascular Disease

This study is open to adults with type 2 diabetes, high blood pressure, and cardiovascular disease. People can join the study if they have these conditions and…

Diabetes Mellitus, Type 2HypertensionCardiovascular Diseases

Estimated

~$10 – $7,500

Boehringer IngelheimNCT07064473

Phase 2

A Phase 2 Study Using Chemoimmunotherapy With Gemcitabine, Cisplatin and Nivolumab in Newly Diagnosed Nasopharyngeal Carcinoma (NPC)

This phase II trial tests effects of nivolumab in combination with chemotherapy drugs prior to radiation therapy patients with nasopharyngeal carcinoma (NPC). …

Stage II Nasopharyngeal Carcinoma AJCC v8Stage III Nasopharyngeal Carcinoma AJCC v8Stage IV Nasopharyngeal Carcinoma AJCC v8

Estimated

~$10 – $5,625

National Cancer Institute (NCI)NCT06064097

Phase 1

A Phase 1/1b Trial of AB801 in Combination With Chemotherapy and PD-1/PD-L1 Blockade in Patients With Cholangiocarcinoma or Pancreatic Adenocarcinoma

This phase I trial tests the safety, side effects, best dose and effectiveness of AB801 in combination with chemotherapy and immunotherapy in treating patients…

Borderline Resectable Pancreatic Ductal AdenocarcinomaLocally Advanced CholangiocarcinomaLocally Advanced Pancreatic Adenocarcinoma+5 more

Estimated

~$10 – $6,250

Jonsson Comprehensive Cancer CenterNCT07619313

Phase 3

A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Assess Efficacy and Safety of REGN7508, a Monoclonal Antibody Against FXI, for Primary Prophylaxis of Cancer-Associated Thrombosis for Participants With Solid Tumors Undergoing Cancer Treatment (ROXI-CAT-I)

This study is researching an experimental drug called REGN7508 (called "study drug"). The study is focused on the prevention of Cancer-Associated Thrombosis (C…

Cancer-Associated Thrombosis (CAT)

Estimated

~$10 – $8,750

Regeneron PharmaceuticalsNCT07410117

Observational

Caring for Dementia Caregivers in Ethnic Immigrant Communities

Many caregivers of people with Alzheimer's disease or other dementias-especially those in immigrant communities who don't speak English well-don't get access t…

No Disease or Condition is Being StudiedStress (Psychology)

Estimated

~$10 – $6,250

University of Southern CaliforniaNCT07550075

Global Prospective Natural History Study of POLG Disease

The PIONEER study is a prospective, natural history study dedicated to characterizing the clinical progression of POLG-related disorders. The research aims to …

PolG, Primary Mitochondrial Myopathy

Estimated

~$10 – $750

The POLG FoundationNCT07775872

Burnout and Safety Assessment for Frontline Clinical Employees in Home Hospital and Brick-and-Mortar Hospital

The goal of this observational study is to learn about burnout and workplace violence among frontline clinicians working in Home Hospital programs compared wit…

Burnout, Healthcare WorkersWorkplace Violence

Estimated

~$10 – $750

Brigham and Women's HospitalNCT07773168

Observational

Visualization of the Colon Through Use of the Magnetic Flexible Endoscope (MFE) in Participants With Inflammatory Bowel Disease (IBD)

In this study, the investigators will test the ability of the Magnetic Flexible Endoscope (MFE) to travel through the colon of people with Inflammatory Bowel D…

Inflammatory Bowel Disease (IBD)Colonoscopy

Estimated

~$10 – $6,250

Vanderbilt University Medical CenterNCT06989424

Phase 1

Phase 1 Study to Determine the Safety and Tolerability of Ziftomenib Combinations for the Treatment of KMT2A-rearranged or NPM1-mutant Relapsed/Refractory Acute Myeloid Leukemia

The safety, tolerability, and antileukemic response of ziftomenib in combination with standard of care treatments for patients with relapsed/refractory acute m…

AMLAML With Mutated NPM1Hematologic Malignancy+9 more

Estimated

~$10 – $8,750

Kura Oncology, Inc.NCT06001788