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Analysis of Prognostic Cell Signaling Factors in Adolescent Idiopathic Scoliosis

The purpose of this study is to identify potential markers for curve progression in adolescent idiopathic scoliosis (AIS). Despite its prevalence and impact on…

Adolescent Idiopathic Scoliosis

Estimated

~$10 – $750

University of Colorado, DenverNCT02315729

Phase 4

Markers of Nephrotoxicity During Treatment With Antibiotic Combinations: A Pragmatic Clinical Trial

Hospitalized patients with suspected or confirmed infection are commonly treated with vancomycin (VN) in combination with either piperacillin-tazobactam (PT) o…

Acute Kidney Injury

Estimated

~$10 – $6,250

University of PennsylvaniaNCT06954129

Observational

The Impact of an Intervention to Reduce Pharmacists' Racial Bias Towards People of Color at Risk of HIV

This study will follow the ADAPT-ITT model to apply the Prejudice Habit Breaking Intervention (PHBI) to pharmacists who have experience with or are willing to …

Bias, ImplicitHIVPre-exposure Prophylaxis

Estimated

~$10 – $6,250

Massachusetts General HospitalNCT06487351

Patient Preferences for Barrett's Esophagus and Esophageal Cancer Screening Tests: A Discrete Choice-Based Conjoint Analysis

This study plans to learn more about what patients think about screening for esophageal cancer (EAC) and Barrett's esophagus (BE); a pre-cancerous condition as…

Gastro Esophageal Reflux DiseaseBarrett Esophagus

Estimated

~$10 – $750

University of Colorado, DenverNCT06693622

Phase 1

A Phase 1 Single- and Multiple-Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SRK-439 in Healthy Adults

A phase 1 study to assess the safety, tolerability, pharmacokinetics, and pharmacodynamics of SRK-439 in healthy adults

Healthy

Estimated

~$10 – $8,750

Scholar Rock, Inc.NCT07444294

Phase 2

A Randomized, Double Blind, Placebo-controlled, Dose Response, Phase II, Multicentre Trial to Evaluate the Efficacy and Safety of Oral AP1189 Administered at the Doses of 40, 70, or 100 mg for 12 Weeks in Combination With Methotrexate, in DMARD-naïve Participants With Early Rheumatoid Arthritis and Active Inflammation.

The study is a randomized, double blind, placebo-controlled, dose response, phase II, multicentre trial to evaluate the efficacy and safety of oral AP1189 admi…

Rheumatoid Arthritis (RA)

Estimated

~$10 – $8,750

SynAct Pharma ApsNCT06671054

Phase 4

Pilot Study of Fisetin to Improve Fatigue Among Older Adult Cancer Survivors

The purpose of this study is to find out if taking a Fisetin supplement can decrease fatigue among older cancer survivors.

Fatigue

Estimated

~$10 – $6,250

Wake Forest University Health SciencesNCT06819254

Phase 1

Lived Experiences Measured Using Ring Study: Single Session Intervention to Motivate Behavioral Change

The goal of this substudy is to determine if a brief single-session-intervention (SSI) coupled with different incentive strategies to support engaging in welln…

Incentives

Estimated

~$10 – $6,250

University of VermontNCT06340841

Observational

Analytic Treatment Interruption in HIV Infection

The goal of this study is to understand the interaction between HIV and the host at the earliest stages when HIV medications are paused. Volunteers with HIV wi…

HIV/AIDS

Estimated

~$10 – $5,625

University of California, San FranciscoNCT04359186

Phase 2

A Phase 2, Open-label, Multicenter Study to Evaluate the Safety, Tolerability, PK, and Efficacy of Vimseltinib in Adults With Active Chronic GVHD After Failure of Prior Systemic Therapy

The purpose of this study is to determine if vimseltinib is safe, tolerable and works effectively to treat adults with active moderate to severe cGVHD. Partici…

Chronic Graft-Versus-Host Disease (cGVHD)

Estimated

~$10 – $8,750

Deciphera Pharmaceuticals, LLCNCT06619561

Undifferentiated Connective Tissue Disease Registry

This registry has been established to gain a better understanding of the clinical and emotional presentations of patients with undifferentiated connective tiss…

Undifferentiated Connective Tissue Disease

Estimated

~$10 – $750

Hospital for Special Surgery, New YorkNCT02234388

Observational

Ablation With Confirmation of Colorectal Liver Metastases (ACCLAIM) Prospective Trial for Microwave Ablation as a Local Cure

To demonstrate that microwave ablation (MWA) of up to 3 hepatic metastases, each with a maximum diameter of ≤ 2.5 cm will result in a 2-year local progression …

Colorectal Liver Metastases

Estimated

~$10 – $7,500

Society of Interventional OncologyNCT05265169