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Low-Intensity Mechanical Stimulation for Hematologic Malignancy Patients

This clinical trial tests the effect of low-intensity mechanical stimulation (LIMS) vibration therapy in patients with hematologic malignancies. Patients with …

Hematopoietic and Lymphoid System Neoplasm

Estimated

~$10 – $7,500

Roswell Park Cancer InstituteNCT05893940

Phase 1

A Phase 1b/2 Open-label Study Evaluating Different MK-6070 and Ifinatamab Deruxtecan (MK-2400)-Based Regimens in First-line Extensive Stage Small Cell Lung Cancer

Researchers are looking for new ways to treat extensive-stage small cell lung cancer (ES-SCLC). ES-SCLC is a type of lung cancer that has spread throughout the…

Small Cell Lung Cancer Extensive Stage

Estimated

~$10 – $8,750

Merck Sharp & Dohme LLCNCT07227597

Phase 2

A Phase 2a Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of MK-8690 in Adult Participants With Moderately to Severely Active Ulcerative Colitis

The purpose of this protocol is to evaluate the efficacy of MK-8690 in participants with moderately to severely active ulcerative colitis. The primary hypothes…

Colitis UlcerativeUlcerative Colitis

Estimated

~$10 – $8,750

Merck Sharp & Dohme LLCNCT07463183

Observational

Investigation on the Bidirectional Cortical Neuroprosthetic System

The Bidirectional Cortical Neuroprosthetic System (BiCNS) consists of NeuroPort Microelectrode Array Systems and NeuroPort Electrodes (Sputtered Iridium Oxide …

TetraplegiaQuadriplegia

Estimated

~$10 – $6,250

Johns Hopkins UniversityNCT03161067

Phase 1

A PHASE 1, NON-RANDOMIZED, OPEN-LABEL, SINGLE-DOSE, PARALLEL GROUP STUDY TO COMPARE THE PHARMACOKINETICS OF ATIRMOCICLIB IN ADULT PARTICIPANTS WITH VARYING DEGREES OF HEPATIC IMPAIRMENT RELATIVE TO PARTICIPANTS WITH NORMAL HEPATIC FUNCTION

The purpose of this study to understand how the study medicine atirmociclib behaves in the body and how safe it is for people with different levels of liver he…

Hepatic ImpairmentHealthy, Hepatic InsufficiencyHealthy Adults

A Phase 2, Open-Label, Randomized, Master Protocol Dose Optimization Study to Evaluate Safety and Efficacy of Multiple Treatment Combinations With Mirvetuximab Soravtansine in Subjects With Ovarian Cancer

Ovarian cancer is a lethal disease with an estimated 310,000 new cases and 200,000 deaths experienced worldwide in 2020. The purpose of this study is to assess…

Registry of Asthma Characterization and Recruitment 3 (RACR3) (CAUSE-02)

This is a multi-center, non-interventional registry to create and maintain a database of participants to serve as a recruitment source for current and future D…

Asthma

Estimated

~$10 – $675

National Institute of Allergy and Infectious Diseases (NIAID)NCT05272241

Phase 2

Investigating the Analgesic Potential of (2R,6R)-HNK in Acute Pain in Healthy Volunteers

Background: Opioid drugs are often prescribed for acute and chronic pain. But these drugs are addictive, and they lead to more than 14,000 overdose deaths in …

Healthy Volunteers

Estimated

~$10 – $7,500

National Center for Complementary and Integrative Health (NCCIH)NCT07504601

Observational

The Vira Platform: A Contextually Triggered Just-in-Time Adaptive Intervention for Opioid Use Disorder

Many patients stop medication-based treatments for Opioid Use Disorder (OUD) prematurely, placing them at increased risk for overdose and death. Providing targ…

Opioid Use DisordermHealthPeer Support

Estimated

~$10 – $6,250

Rhode Island HospitalNCT07778394

Phase 2

Phase II Haploidentical Hematopoietic Stem Cell Transplantation for Participants With Germline RUNX1 Associated Hematologic Malignancies

Background: Some blood cancers can be caused by germline variants (changes) in a person s RUNX1 gene. Germline variants are genetic inherited changes a person…

Core Binding Factor Alpha SubunitsHematologic NeoplasmsLeukemia+1 more

Estimated

~$10 – $5,625

National Cancer Institute (NCI)NCT07524530

Phase 3

A Phase 3, Open-label Study of Ifinatamab Deruxtecan Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC) (IDeate-Prostate01)

Researchers are looking for new ways to treat metastatic castration-resistant prostate cancer (mCRPC). Researchers have designed a study medicine called ifinat…

Prostate CancerProstatic Neoplasms

Estimated

~$10 – $8,750

Merck Sharp & Dohme LLCNCT06925737

The Experience and Management of Cancer Screening-Related Anxiety in Fanconi Anemia: an Ethnographic Study

Background: Fanconi anemia (FA) is a rare, inherited cancer syndrome. FA causes a range of physical issues. Children with FA may have abnormal features; these…

Fanconi Anemia

Estimated

~$10 – $675

National Cancer Institute (NCI)NCT06744283