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Women's Ischemia Syndrome Evaluation (WISE) - Coronary Microvascular Dysfunction (CMD) and Heart Failure With Preserved Ejection Fraction (HFpEF)

The Women's Ischemia Study Evaluation (WISE), a cohort study of over 1000 women, has made many contributions to the understanding of cardiovascular disease. A …

Microvascular Coronary DysfunctionCardiovascular Disease

Estimated

~$10 – $750

Cedars-Sinai Medical CenterNCT02582021

Phase 2

A Phase II Study of Inotuzumab Ozogamicin Followed by Blinatumomab for Ph-Negative, CD22-Positive B-Lineage Acute Lymphoblastic Leukemia in Newly Diagnosed Older Adults or Adults With Relapsed or Refractory Disease

This phase II trial studies how well inotuzumab ozogamicin and blinatumomab with or without ponatinib work in treating patients with CD22-positive B-lineage ac…

B Acute Lymphoblastic Leukemia, Philadelphia Chromosome NegativeRecurrent B Acute Lymphoblastic LeukemiaRefractory B Acute Lymphoblastic Leukemia

Estimated

~$10 – $5,625

National Cancer Institute (NCI)NCT03739814

Technical and Translational Development of Cardiovascular MRI (CMR)

Background: Magnetic resonance imaging (MRI) is an important non-invasive tool to study and diagnose cardiovascular disease. MRI scanners use strong magnetic …

Normal and Abnormal Cardiovascular Physiology

Estimated

~$10 – $675

National Heart, Lung, and Blood Institute (NHLBI)NCT03581318

Phase 1

A Phase 1/2, Open-Label, Dose-Escalation and -Expansion Study of the Bruton Tyrosine Kinase Targeted Protein Degrader BGB-16673 in Patients With B-Cell Malignancies

Study consists of two main parts to explore tacabrutideg recommended dosing, a Phase 1 monotherapy dose finding comprised of monotherapy dose escalation and mo…

B-cell MalignancyMarginal Zone LymphomaFollicular Lymphoma+6 more

Estimated

~$10 – $7,500

BeOne MedicinesNCT05006716

Phase 1

Phase I Clinical Trial to Study the Safety and After-effects of Transcranial Magnetic Stimulation (TMS) Using A High-density Theta Burst Stimulation (hdTBS) Paradigm

Background: Transcranial magnetic stimulation (TMS) uses magnetic pulses to affect brain activity. A type of TMS called theta burst stimulation (TBS) is appro…

Healthy Volunteers

Estimated

~$10 – $5,625

National Institute on Drug Abuse (NIDA)NCT06868914

Phase 3

A Randomized, Double-masked, Active-controlled, Multi-center, Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal Tabirafusp Tedromer 5 mg Compared With Intravitreal Aflibercept 2 mg in Participants With Visual Impairment Secondary to Diabetic Macular Edema (DME) - ALTO

A Study to Evaluate the Efficacy and Safety of Tabirafusp Tedromer Compared to Aflibercept in Participants with Diabetic Macular Edema - ALTO

Diabetic Macular Edema (DME)

Estimated

~$10 – $8,750

Kodiak Sciences IncNCT07734844

Phase 2

preEMBER: A Phase 2, Open-label Study Evaluating Imlunestrant in Premenopausal Women With Estrogen Receptor-Positive, HER2-Negative Breast Cancer

This study will include two groups of patients: Cohort 1 and Cohort 2. Cohort 1: will help researchers learn how a medicine called imlunestrant (LY3484356) af…

Breast Neoplasms

Estimated

~$10 – $7,500

Eli Lilly and CompanyNCT07287098

Observational

Buprenorphine Implementation at Syringe Services Programs To Reduce Overdoses: A Type 1 Hybrid Effectiveness-Implementation Trial

This study is testing whether offering buprenorphine treatment directly at syringe service programs (SSPs) helps more people start and stay in treatment for op…

Opioid Use DisorderOpioid Use Disorder, SevereOpioid Use Disorder, Moderate

Estimated

~$10 – $6,250

Montefiore Medical CenterNCT07631598

Phase 3

A Phase 3, Double-Blind, Randomized, Placebo-Controlled Study of Baricitinib to Preserve Beta Cell Function in Participants Newly Diagnosed With Type 1 Diabetes Aged ≥1 to <36 Years

The purpose of this study is to find out if baricitinib can preserve beta-cell function in participants newly diagnosed with type 1 diabetes. Participation in …

Diabetes Mellitus, Type 1

Estimated

~$10 – $7,500

Eli Lilly and CompanyNCT07222332

Observational

First-In-Human Trial of Miniature In-Line, Pressure-Cycled, Emergency Respirator Device in Human Organ Donors

This first-in-human pilot study will test an investigational miniature breathing device called the Hope inVent. The device is a small, single-use, in-line resp…

Brain DeathRespiration, Artificial

Estimated

~$10 – $5,625

National Institutes of Health Clinical Center (CC)NCT07768215

Phase 2

Randomized Phase II Study of Belumosudil vs. Placebo for Preemptive Treatment of Chronic Graft Versus Host Disease

This phase II trial compares the effect of belumosudil to a placebo in treating patients with chronic graft versus host disease. Chronic graft versus host dise…

Chronic Graft Versus Host Disease

Estimated

~$10 – $6,250

Fred Hutchinson Cancer CenterNCT05996627

An Observational Study of Visual Attention, Object Recognition, and Eye Movements in Healthy Volunteers

Background: Vision is vital for many of our daily activities. Researchers want to learn more about how we aim our eyes (that is, what images, such as faces, i…

Healthy Volunteer

Estimated

~$10 – $675

National Eye Institute (NEI)NCT07756853