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A Phase 1, Open-label, 3-Part Study to Assess Potential Drug-Drug Interactions of E2086 When Coadministered Orally With Itraconazole, Carbamazepine, Midazolam, Dextromethorphan, Bupropion, or Combined Oral Contraceptives in Healthy Subjects

The primary purpose of this study is to assess potential drug-drug interactions of E2086 when coadministered orally with Itraconazole, Carbamazepine, Midazolam…

Healthy Volunteers

Estimated

~$10 – $8,750

Eisai Inc.NCT07766369

Natural History and Structural Functional Relationships in Fabry Renal Disease Natural History, Structural Functional Relationships and Determinants of Renal Structural Responses (Changes) With Enzyme Replacement Therapy in Fabry Disease

The investigators will perform a study with two major components. The first is a natural history study of untreated Fabry patients. This study component will d…

Fabry Disease

Estimated

~$10 – $750

University of MinnesotaNCT01581424

Observational

Textured Insoles to Restore Sensorimotor Function in Patients With Plantar Fasciopathy

This study will evaluate the immediate effects of wearing textured insoles on gait, postural control, and sensorimotor function in adults with plantar fasciopa…

Plantar Fasciopathy

Estimated

~$10 – $7,500

Jennifer XuNCT07765082

Phase 2

A Phase 2a, Randomized, Double-Blind, Placebo-Controlled Dose Comparison and Exploratory Efficacy Study of Orally Administered SAT-3247 in Ambulatory DMD Patients

Phase 2a trial of SAT-3247 in ambulatory DMD patients aged ≥ 7 and \< 10 years. The trial has two parts. In Part 1, the trial will study two doses of SAT-3247 …

Duchenne Muscular DystrophyDuchenneDMD+2 more

Estimated

~$10 – $8,750

Satellos Bioscience, Inc.NCT07287189

Phase 2

Minimal Residual Disease Guided Maintenance Therapy With Belantamab Mafodotin and Lenalidomide After Autologous Hematopoietic Cell Transplantation in Patients With Newly Diagnosed Multiple Myeloma

To increase the conversion rate from MRD-positive to MRD-negative CR in patients with newly diagnosed multiple myeloma (NDMM) receiving post-transplant mainten…

Myeloma Multiple

Estimated

~$10 – $6,250

M.D. Anderson Cancer CenterNCT05091372

Observational

Screening & TReatment fOr Perinatal WomeN With PTSD in Substance Use Care SettinGs in Arkansas (STRONG Moms)

The goal of this study is to examine the feasibility and acceptability of providing Written Exposure Therapy (WET), a brief, evidence-based therapy for post-tr…

Written Exposure Therapy

Estimated

~$10 – $6,250

University of ArkansasNCT07759882

Phase 3

A Phase 3 Multicenter, Randomized, Double-Blind, Placebo Controlled Trial to Evaluate Efficacy and Safety of Mezagitamab (TAK-079) in Study Participants With Primary IgA Nephropathy in Combination With Stable Background Therapy

Immunoglobulin A nephropathy (IgAN) is a kidney condition. It happens when the body's immune system creates groups of proteins (called immune complexes) that b…

A Phase III, Randomized, Multicenter, Parallel-group, Non-inferiority, Open-label Study Evaluating the Efficacy, Safety, and Tolerability of Cabotegravir Ultra Long-acting Plus Rilpivirine Ultra Long-acting or Cabotegravir Long-acting Plus Rilpivirine Long-acting in Adults and Adolescents With HIV Who Are Virologically Suppressed on ART

This study compares the efficacy, safety and tolerability of CAB ULA and RPV ULA administered with CAB long acting (LA) and RPV LA administered in adults and a…

HIV Infections

Estimated

~$10 – $7,500

ViiV HealthcareNCT07650916

Phase 4

Empiric vs Selective Medical Therapy for Calcium Oxalate Stone Prevention: A Randomized Controlled Trial

This single-center randomized controlled trial at Mount Sinai West will enroll 80 patients undergoing percutaneous nephrolithotomy for calcium oxalate stones. …

Kidney Stones

Estimated

~$10 – $6,250

Icahn School of Medicine at Mount SinaiNCT07225764

Phase 2

A Randomized, Double-blind, Placebo-controlled Study to Evaluate the Effects of Intranasal Oxytocin in Adults With Binge-eating Disorder

This study evaluates the impact of intranasal oxytocin vs placebo in patients with binge eating disorder or episodes of binging. We hypothesize that 8 weeks of…

Binge-eating Disorder

Estimated

~$10 – $6,250

Massachusetts General HospitalNCT05664516

Development of Brief Positive Affect Treatment (PAT) for Caregivers of Patients With Advanced Cancer

To learn more about the experience and wellbeing of people who provide care for cancer patients.

Cancer

Estimated

~$10 – $750

M.D. Anderson Cancer CenterNCT05904782

Role of Synaptic Density in Mediating the Relation Between Social Disconnection and Late-life Suicide Risk

The purpose of this research study is to examine the effect of social connectedness on the brain. Study procedures include one Magnetic Resonance Imaging (MRI)…

Social Disconnection

Estimated

~$10 – $750

Yale UniversityNCT06705348