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27,354 recruiting studies available now

A Phase II Study of High Dose Radiotherapy in Combination With Pembrolizumab Plus Chemotherapy in Patients With PD-L1 Positive Metastatic Triple Negative Breast Cancer

This phase II trial tests how well radiation therapy with pembrolizumab and chemotherapy (paclitaxel or nab-paclitaxel or carboplatin and gemcitabine) works in…

Anatomic Stage IV Breast Cancer AJCC v8Metastatic Triple-Negative Breast Carcinoma

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Emory UniversityNCT06492759

Phase 1

Phase I/II Open Label Trial of Intravenous Sodium Thiosulfate (Pedmark®) as Otoprotectant in Adults Receiving Cisplatin Chemotherapy (STOP-CIS)

The purpose of this study is to assess the safety and effectiveness of a drug called Pedmark® sodium thiosulfate (STS) in reducing hearing impairment with stan…

Solid Tumor MalignanciesTesticular CancerHead and Neck Cancer+1 more

Estimated

~$150 – $3,000

Actual pay is set by the research site.

University of ArizonaNCT07407582

Phase 2

Pregnenolone as a Treatment for Cannabis Intoxication

The present study will characterize the ability of pregnenolone to reverse the acute intoxication and associated symptoms of cannabis. Healthy adults with a hi…

Cannabis Intoxication

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Johns Hopkins UniversityNCT07216690

Phase 1

Study of LAM561 Acid in Pediatric Patients With Malignant Glioma and Other Advanced Solid Tumors

An open label, non-randomized study in pediatric patients with advanced high-grade gliomas and other solid tumors. The study will be performed in two phases: …

High-grade GliomaSolid Tumor, Unspecified, Child

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Laminar PharmaceuticalsNCT04299191

Observational

Impact of Suture Type on Pigment Disturbances in Patients of Skin of Color: A Prospective, Randomized Split-wound Study

The present study assesses if dissolvable (fast gut) or non-dissolvable (polypropylene) epidermal sutures produce better cosmetic results in terms of dyspigmen…

Scar

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Melissa Pugliano-MauroNCT05408117

Observational

Cardiac Anodal Biphasic Pacing

The goal of this study is to test a new pacing method called anodal biphasic pacing (ABP) to determine if this pacing works as well-or better-than current paci…

Cardiac Pacing

Estimated

~$10 – $750

Actual pay is set by the research site.

Boston Medical CenterNCT07173777

Observational

A Prospective, Randomized, Single-blind, Controlled, Multi-center Study to Assess the Safety and Performance of MagnetOsTM Compared to Autogenous Bone Graft in Patients Undergoing Hindfoot or Ankle Fusions

This is a phase IV post-marketing study for MagnetOs Putty and MagnetOs Easypack Putty. MagnetOs is a synthetic bone graft extender product that is routinely u…

Ankle Arthrodesis or ArthroplastyHindfoot FusionAnkle Deformity+3 more

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Kuros Biosurgery AGNCT07225751

Phase 4

Comparison of Outcomes of Management of Bowel Obstruction

The Comparison of Outcomes of Management of Bowel Obstruction (COMBO) trial is a patient-level randomized trial of a short course of dexamethasone + supportive…

Adhesive Small Bowel Obstruction

Estimated

~$25 – $1,000

Actual pay is set by the research site.

University of WashingtonNCT07084441

Phase 2

HP-211 Safety and Proof of Concept Dose Ranging Study in Patients With Type 2 Diabetes

Blood sugar levels are controlled by insulin, a hormone made by cells in the pancreas. After a meal, carbohydrates are broken down into glucose which is absorb…

Type 2 Diabetes

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Housey Healthcare ULCNCT07546929

Observational

Mechanisms of Anabolic Osteoporosis Therapy

The aim of this study is to investigate the effect of romosozumab on bone cells during early and late phases of treatment.

Osteoporosis, Postmenopausal

Estimated

~$10 – $750

Actual pay is set by the research site.

Massachusetts General HospitalNCT05688969

Developmental Effects of Antenatal Exposure to Antipsychotics

The goal of this observational study is to learn about maternal psychiatric course and infant development in pregnant individuals with severe mental illness, c…

AntipsychoticsPregnancy

Estimated

~$10 – $750

Actual pay is set by the research site.

Icahn School of Medicine at Mount SinaiNCT06049953

Phase 1

Evaluation of the Safety, Tolerability and Efficacy of Regenerative Therapy for the Treatment of Various Chronic and Acute Conditions

This multi-arm, multi-site study investigates the safety, tolerability, and efficacy of stem cell therapy for the treatment of various acute and chronic condit…

Autoimmune DiseasesCardiovascular DisordersDiabetes Complications+8 more

Estimated

~$500 – $10,500

Actual pay is set by the research site.

Thomas Advanced Medical LLCNCT04684602