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27,273 recruiting studies available now

A Phase I Study of Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, and Other Hematologic Malignancies

Background: Blood cancers (such as leukemias) can be hard to treat, especially if they have mutations in the TP53 or RAS genes. These mutations can cause the …

Malignancy, HematologicNeoplasms, HematologicNeoplasms, Hematopoietic+8 more

Estimated

~$150 – $2,700

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT06904066

Assessing the Impact of Perceptions of Unpredictability on Objective Measures of Food Consumption and Metabolism: A Natural History Study

Background: Many people in the United States are overweight or obese. This natural history study will look into how life events during childhood can impact ea…

Healthy VolunteerObestity

Estimated

~$10 – $675

Actual pay is set by the research site.

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NCT06690294

Phase 2

Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjogren's Disease Phase IIa Open-Label Clinical Trial and Associated Mechanistic Studies

Background: Sjogren disease is an autoimmune disease - that is, a disease that causes the body's immune system to attack its own organs and tissues. Sjogren d…

Sjogren's Syndrome

Estimated

~$75 – $1,800

Actual pay is set by the research site.

National Institute of Dental and Craniofacial Research (NIDCR)NCT07281456

BIO-FUNCTION for NRM Prediction in SCTCT: Assessing Biological and Functional Reserve to Predict Non-Relapse Mortality in Stem Cell Transplant and Cell Therapy

The purpose of this research is test if combination of physical tests and blood tests drawn before SCTCT can predict NRM.

Mortality Prediction

Estimated

~$10 – $750

Actual pay is set by the research site.

Henry Ford Health SystemNCT07769151

Phase 3

A Phase 3, Double-Blind, Randomized, Two-Period, Multicenter, Placebo-Controlled, Efficacy and Safety Study of JNT-517 for the Treatment of Participants With Phenylketonuria

This Phase 3 study will evaluate the safety, effectiveness, tolerability, and how the body processes JNT-517 in children, adolescents, and adults with phenylke…

Phenylketonuria

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Otsuka Pharmaceutical Development & Commercialization, Inc.NCT06971731

BOdygUardian MOnitoriNg for ReCurrencE of AF (BOUNCE-AF)

The DISRUPT-AF Registry is an observational, prospective, multi-center, non-randomized, real-world registry designed to obtain clinical experience with the FAR…

Atrial Fibrillation (AF)

Estimated

~$10 – $750

Actual pay is set by the research site.

Heart Rhythm Clinical and Research Solutions, LLCNCT07671677

Evaluation of the Clinical Spectrum of Diabetes and Obesity in Youth and Adults

Background: Diabetes and obesity are chronic diseases. They can affect blood flow and how the body processes nutrients, and complications over time can lead t…

ObesityDiabetesMetabolic Disorders

Estimated

~$10 – $675

Actual pay is set by the research site.

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NCT07388537

Phase 1

Phase I/II Trial of Pacritinib, a Kinase Inhibitor of CSF1R, IRAK1, JAK2, and FLT3, in Adults and Pediatric Participants 12 Years of Age or Older With Myelodysplastic Syndromes or Myelodysplastic/Myeloproliferative Neoplasms

Background: Myelodysplastic syndrome (MDS) and myelodysplastic/myeloproliferative neoplasm (MDS/MPN) are blood disorders that can cause serious complications …

Myelodysplastic Syndromes

Estimated

~$150 – $2,700

Actual pay is set by the research site.

National Cancer Institute (NCI)NCT06303193

Phase 1

Open Label, Multicenter, Dose-escalation and Cohort-expansion Phase I/IIA Trial of STC-1010, an Immunotherapy, in Patients With Unresectable Locally Advanced or Metastatic Colorectal Cancer (CRC) - BreAK CRC Trial (BreAK for Brenus Anti-cancer)

This is a phase I/IIA, first-in-human (FIH), two-part, open-label, multicenter study to characterize the safety, tolerability profile, and clinical efficacy of…

Unresectable Metastatic Colorectal CancerUnresectable Locally Advanced Colorectal Cancer

Estimated

~$150 – $4,200

Actual pay is set by the research site.

Brenus PharmaNCT06934538

Observational

PrEcision Pacing in HFpEF: the PEP-HFpEF Trial

The PEP-HFpEF study is a prospective, single-center mechanistic study evaluating personalized heart rate pacing (myPACE) in patients with heart failure with pr…

Heart Failure and Preserved Ejection FractionHeart Failure New York Heart Association Class IIIHeart Failure New York Heart Association (NYHA) Class II

Estimated

~$10 – $750

Actual pay is set by the research site.

Tufts Medical CenterNCT07864558

Phase 4

Risk of Acute Complications With Rocuronium vs Cisatracurium in Patients With Chronic Kidney Disease

The purpose of the study is to determine which combination of neuromuscular blocking agent and reversal agent is safer to use during anesthesia for patients wi…

Post Operative Pulmonary ComplicationsNeuromuscular BlockadeGeneral Anesthesia

Estimated

~$25 – $1,000

Actual pay is set by the research site.

The University of Texas Medical Branch, GalvestonNCT07203287

Phase 3

A Phase 3, Multicenter, Clinical Study to Evaluate the Efficacy and Safety of Safusidenib Erbumine in Participants With Isocitrate Dehydrogenase 1 (IDH1)-Mutant Glioma

This is a 3-part study. The purpose of Part 1 of the study is to evaluate the efficacy, safety, and pharmacokinetic (PK) characteristics of safusidenib in part…

GliomaAstrocytoma, Grade IVIDH1-mutant Glioma+5 more

Estimated

~$50 – $2,100

Actual pay is set by the research site.

Nuvation Bio Inc.NCT05303519