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Pivotal TRIal to Evaluate TraNsvenous TrIcuspid Valve ReplacemenT With Lux Valve Plus System in Patients With Severe or Greater Tricuspid Regurgitation - Clinical SafetY and Effectiveness

The goal of this clinical trial is to learn if LuX-Valve Plus system works to treat symptomatic subjects with at least severe tricuspid regurgitation (TR). It …

Tricuspid Regurgitation (TR)

Estimated

~$10 – $1,050

Actual pay is set by the research site.

Jenscare Innovation Inc.NCT07454980

Observational

Effect of Acute Intermittent Hypoxia in Healthy Individuals

The use of acute intermittent hypoxia (AIH) has been examined in animal and human studies to gain an understanding of its effect on spinal excitability and syn…

Healthy

Estimated

~$10 – $1,125

Actual pay is set by the research site.

Shirley Ryan AbilityLabNCT04691518

Observational

Addressing Sleep Duration, Regularity, and Efficiency: A Multidimensional Sleep Health Intervention for Improving Cardiometabolic Health (The DREAM Study)

The purpose of this randomized clinical trial is to evaluate the impact of a multidimensional sleep health promotion intervention on blood pressure, glycemic c…

Blood Pressure

Estimated

~$10 – $750

Actual pay is set by the research site.

Columbia UniversityNCT06285968

Modeling Adherence to Preventive Swallowing Exercises in Head and Neck Cancer

This trial uses blood tests and questionnaires to study how well participants with head and neck cancer that has spread to other places in the body adhere to s…

Carcinoma of Unknown PrimaryClinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8+28 more

Phase 2

A Phase 2, Multicenter, Double-Blind, Randomized, Controlled Trial of the Safety and Immunogenicity of a Self-Amplifying mRNA COVID-19 Vaccine in Adult Hematopoietic Cell Transplant Recipients

This phase IIb trial compares the effect of LUNAR-COV19 vaccine to Comirnaty vaccine in treating adult patients who have received a hematopoietic cell transpla…

Hematopoietic and Lymphatic System Neoplasm

Estimated

~$75 – $2,000

Actual pay is set by the research site.

Fred Hutchinson Cancer CenterNCT07390968

Phase 1

An Open-label, Pharmacokinetic and Safety Trial Optimizing PreTerm Infant Ampicillin Dosing

The goal of this clinical trial is to learn if preterm infants who are prescribed antibiotics shortly after birth can safely receive a shorter course of antibi…

Early Onset SepsisPreterm NeonatesNICU+2 more

Estimated

~$150 – $3,000

Actual pay is set by the research site.

Duke UniversityNCT07610486

LXR as a Novel Therapeutic Target in DR

Results from large clinical trials demonstrate a strong association between lipid abnormalities and progression of the most common microvascular complication, …

Diabetic Retinopathy

Estimated

Pay not disclosed — ask the coordinator

University of Alabama at BirminghamNCT03403686

Phase 1

A Phase 1 Trial of CIML NK Cell Infusion for Myeloid Disease Relapse After Hematopoietic Cell Transplantation

This research study is studying cytokine induced memory-like natural killer (CIML NK) cells combined with IL-2 in adult patients (18 years of age or older) wit…

Acute Myeloid LeukemiaMyelodysplastic SyndromesMyeloproliferative Neoplasm+1 more

Estimated

~$150 – $4,500

Actual pay is set by the research site.

Dana-Farber Cancer InstituteNCT04024761

Observational

Supporting Practices In Respecting Elders Phase 2

This study consists of three aims focused on examining the feasibility of adding the Geriatric Resources and Assessment for the Care of Elders (GRACE) model to…

AgingPreventive CareMultimorbidity+1 more

Estimated

~$10 – $750

Actual pay is set by the research site.

Massachusetts General HospitalNCT07166861

Phase 3

A Multi-center, Open-label, Single-arm Study to Evaluate the Efficacy and Safety of Oral Rilzabrutinib in Adults With Immune Thrombocytopenia (ITP) Who Failed First-line Treatment

This is a multinational, open label, single arm study that will evaluate the impact of early multi-immune modulation with rilzabrutinib in adult ITP patients w…

Immune Thrombocytopenia

Estimated

~$50 – $2,250

Actual pay is set by the research site.

SanofiNCT07007962

Phase 2

A New Intervention to Improve Function in Veterans With Anxiety and Depression

Anxiety and depression symptoms occur at high rates in Veteran populations and can significantly impact function, compromising the ability to work and to succe…

Anxiety and Depression

Estimated

~$75 – $1,800

Actual pay is set by the research site.

VA Office of Research and DevelopmentNCT06188923

Phase 2

Preoperative Tranexamic Acid (TXA) to Prevent Bleeding in Patients Undergoing Major Colorectal Surgery

The goal of this prospective pragmatic randomized clinical trial is to determine if preoperative administration of tranexamic acid (TXA) reduces bleeding durin…

BleedingColorectal DisordersThromboembolism+1 more

Estimated

~$75 – $3,000

Actual pay is set by the research site.

Kristen BanNCT06657924