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26,706 recruiting studies available now

Oral Methadone In Cardiac Surgery

The purpose of this study is to compare the effects of administration of oral methadone preoperatively and intravenous methadone upon induction of general anes…

Pain, PostoperativeAnesthesiaCardiac Surgery

Estimated

~$10 – $6,250

Mayo ClinicNCT07221617

Phase 3

aPCC and Emicizumab Safety Study in Congenital Hemophilia A Patients With Inhibitors (SAFE Study: Safety of aPCC Following Emicizumab Prophylaxis)

The purpose of the aPCC-emicizumab safety study is to investigate the hemostatic efficacy as measured by thrombin generation, of a low personalized dose of aPC…

Hemophilia A

Estimated

~$10 – $6,250

Emory UniversityNCT04563520

Phase 1

A Phase 1 Open-Label Safety and Immunogenicity Trial of OCU500, ChAd36 Vector Encoding SARS-CoV-2 Spike, A Next-Generation SARS-CoV-2 Booster Vaccine Via Intranasal and Inhalational Routes, in Previously Vaccinated Adults

This phase 1 randomized, open-label, dose-escalation clinical trial evaluates the safety and immunogenicity of OCU500, a ChAd36 Vector Encoding SARS-CoV-2 Spik…

COVID-19

Estimated

~$10 – $5,625

National Institute of Allergy and Infectious Diseases (NIAID)NCT07536308

Phase 2

A Phase 2, Double-blind, Placebo-Controlled Study to Evaluate LY3537021 for the Treatment of Chemotherapy-Induced Nausea and Vomiting in Adult Participants With Malignant Disease

The purpose of this study is to check how well LY35327021 works and how safe it is for controlling nausea and vomiting caused by chemotherapy. Participants who…

NauseaVomitingDrug-Related Side Effects and Adverse Reactions+1 more

Estimated

~$10 – $7,500

Eli Lilly and CompanyNCT07169851

Phase 2

A Phase II, Multi-site, Open-label, Dose-titration Trial to Investigate the Safety, Tolerability, Pharmacokinetics, and Efficacy of Lu AG13909 in Adults With Cushing's Disease

This trial will evaluate the effects of Lu AG13909 in adult participants with Cushing's disease (CD). CD is a rare and serious disorder where the body makes to…

Cushing's Disease

Estimated

~$10 – $7,500

H. Lundbeck A/SNCT06471829

Observational

Superior Venous Access: Single Lumen Midline Catheter vs Ultrasound Guided Peripheral IV as Performed by Bedside Emergency Department Registered Nurses, A Randomized Clinical Trial

Obtaining intravenous (IV) access is one of the most common procedures performed in the emergency department (ED). IV access is necessary for many aspects of p…

Difficult Vein AccessEmergency Department PatientsNurses Role+6 more

Estimated

~$10 – $6,250

Albany Medical CollegeNCT07779317

Observational

Effect of Increasing Lean Beef Intake as Part of a Healthy Meal Plan on Glycemic Control in Adolescents With Polycystic Ovary Syndrome (PCOS)/Polyendocrine Metabolic Ovarian Syndrome (PMOS)

This pilot randomized controlled study will plan to enroll 36 adolescent females with Polycystic Ovary Syndrome (PCOS)/Polyendocrine Metabolic Ovarian Syndrome…

PCOS (Polycystic Ovary Syndrome)Obese AdolescentsOverweight (Without Type 2 Diabetes) With Weight-related Comorbidities+5 more

Estimated

~$10 – $6,250

Texas A&M UniversityNCT07780188

Observational

Maintaining Continuous Medicaid Coverage for Eligible Children in New Jersey

The study introduces a bedside intervention assisting families with the enrollment or re-enrollment process through patient direct contact with NJFamily Care a…

Pediatric Uninsured Emergency VisitsEmergencies

Estimated

~$10 – $7,500

Hackensack Meridian HealthNCT07594782

Phase 3

A Phase IIIb Study to Characterize the Efficacy and Safety of Adjuvant Ribociclib Plus Endocrine Therapy in a Close-to-clinical Practice Patient Population With HR+ HER2- Early Breast Cancer (Adjuvant WIDER)

The purpose of this open-label, multicenter, phase IIIb, single-arm study is to characterize the efficacy and safety of the combination of ribociclib and stand…

Early Breast Cancer

Estimated

~$10 – $8,750

Novartis PharmaceuticalsNCT05827081

Phase 1

A Phase 1, Open-label, Dose Escalation and Dose Expansion Study for LNCB74, a B7-H4 Targeted Antibody Drug Conjugate, as Monotherapy in Participants With Advanced Solid Tumors

This is an open-label, phase 1, dose escalation and dose expansion study to determine safety and tolerability, and to determine the maximum tolerated dose and …

Ovarian CancerBreast CancerEndometrial Cancer+3 more

Estimated

~$10 – $8,750

NextCure, Inc.NCT06774963

Phase 4

Novel Serotype Alert: Investigate New Pneumococcal Conjugate Vaccines for Inducing Cross-protection Against Newly Discovered Serotype 33E and Putative Novel Serogroup 33 Serotypes

The goal of this study is to learn whether different types of vaccines to prevent bacterial infections are able to effectively create antibodies that defend ag…

VaccinePneumococcal Disease

Estimated

~$10 – $6,250

University of Alabama at BirminghamNCT07135453

Phase 2

A Phase 2 Trial of SX-682 and Atezolizumab in Patients With Advanced NSCLC Who Progressed on Prior Chemotherapy and Immune Checkpoint Inhibitor (ICI) Therapy

This phase II trial tests how well SX-682 and atezolizumab works for the treatment of non-small cell lung cancer (NSCLC) that may have spread from where it fir…

Advanced Lung Non-Small Cell CarcinomaMetastatic Lung Non-Small Cell CarcinomaRecurrent Lung Non-Small Cell Carcinoma+2 more

Estimated

~$10 – $6,250

University of WashingtonNCT07322341