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Blood Flow Regulation and Neuromuscular Function Post-Stroke
The muscles of stroke survivors can fatigue faster compared to muscles in people who have not had a stroke, which can limit how long a person with stroke can p…
Time-Restricted Eating and Cancer: Clinical Outcomes, Mechanisms, and Moderators
The purpose of this study is to test whether the timing of meals can improve treatment adverse events, influence tumor biology and alter a person's mood and be…
The United States Patent Ductus Arteriosus Registry
The objective of this study is to demonstrate the continued safety and efficacy in a real-world setting of transcatheter device closure of the PDA in premature…
MRI-Guided Cryoablation for Focal Native Prostate Cancer
The purpose of this research is to collect data about the MRI cryoablation procedure your doctor(s) would normally perform in order to treat the participants f…
Image-Based Functionally Adapted Radiation Therapy for Lung Cancer
The purpose of this research study is to explore using MRI scans with xenon to better image lung function, how lung function changes after radiation therapy, a…
MyPEEPS LITE Trial
This study will use community-informed advertisements and messages through electronic methods to recruit and retain a large (N=3,200), diverse national sample …
An International, Multi-centre, Randomized Controlled Trial to Assess Transfusion Thresholds in Younger Patients Undergoing Cardiac Surgery
TRICS-IV is an international, multi-centre, open-label randomized controlled trial of two commonly used transfusion strategies in moderate to high risk patient…
Phase I Multicenter Study of Ruxolitinib and Duvelisib in Relapsed or Refractory T- or NK-Cell Lymphomas
This study will test the safety of ruxolitinib, given at one dose that does not change, and duvelisib, given at different doses, to find out what effects, if a…
Investigation on the Bidirectional Cortical Neuroprosthetic System
The Bidirectional Cortical Neuroprosthetic System (BiCNS) consists of NeuroPort Microelectrode Array Systems and NeuroPort Electrodes (Sputtered Iridium Oxide …
Defining the Risk of Ventricular Tachycardia in Genetic Forms of Early-onset Atrial Fibrillation
The goal of this observational study is to determine if electrophysiologic mapping and cardiac MRI can help identify patients that have genetic forms of cardio…
Adipocyte-Derived Extracellular Vesicles; Novel Biomarker and Mediator of Obesity-Related Endothelial Dysfunction
Changes in adipose tissue biology are now recognized as a key factor underlying the increased risk of metabolic and cardiovascular disease with obesity. Clinic…
Eosinophils and Inflammation, an Expanded Study
The purpose of this study is to elucidate the mechanisms underlying eosinophil growth, survival, migration, and function and to investigate and further charact…